Informations générales (source: ClinicalTrials.gov)
Epidemiological, Clinical and Biological Characteristics and Therapeutic Management of ICU Patients With Severe Acute Exacerbation of COPD. Evaluation of Prognosis and Factors Associated With Survival.
Observational [Patient Registry]
Alexis FERRE (Voir sur ClinicalTrials)
octobre 2022
avril 2028
16 septembre 2025
The objective of this prospective observational study is to describe the epidemiological,
clinical and biological characteristics of admitted patients in ICU for severe acute
exacerbation of COPD, to assess the different therapeutics used, to evaluate the
prognosis of patients with short, medium and long term ( 1 year) and the various factors
associated with survival in ICU
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CH DE VERSAILLES SITE ANDRE MIGNOT | alexis Ferre | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| CH Le Mans - 72037 - Le Mans - France | Jean Christophe CALLAHAN | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
1. Age ≥ 40 years old
2. COPD documented or strongly suspected
- Chronic respiratory symptoms (dyspnoea, cough and/or sputum)
- Exposure to a known risk factor for COPD (such as tobacco smoke)
- If available, respiratory function tests showing non- or partially reversible
obstructive syndrom (post-bronchodilator ratio FEV1/CV < 0.7)
3. Severe acute exacerbation, defined as a worsening of the patient's usual respiratory
symptoms with signs of acute respiratory distress (polypnoea ≥ 30 cycles.min-1 or
use of accessory respiratory muscles) and/or hypercapnic acidosis (with PaCO2 ≥ 45
mmHg and pH ≤ 7.35)
4. Admission to an ICU, a step-up unit or a respiratory care unit
1. Age ≥ 40 years old
2. COPD documented or strongly suspected
- Chronic respiratory symptoms (dyspnoea, cough and/or sputum)
- Exposure to a known risk factor for COPD (such as tobacco smoke)
- If available, respiratory function tests showing non- or partially reversible
obstructive syndrom (post-bronchodilator ratio FEV1/CV < 0.7)
3. Severe acute exacerbation, defined as a worsening of the patient's usual respiratory
symptoms with signs of acute respiratory distress (polypnoea ≥ 30 cycles.min-1 or
use of accessory respiratory muscles) and/or hypercapnic acidosis (with PaCO2 ≥ 45
mmHg and pH ≤ 7.35)
4. Admission to an ICU, a step-up unit or a respiratory care unit
1. Known asthma (according to the criteria of the international "Global initiative for
asthma" guidelines)
2. Patient refusal to participate (information note, application for non-opposition)