Informations générales (source: ClinicalTrials.gov)

NCT06263868 En recrutement
First Observatory of Precocious and Advanced Puberty in Private Healthcare. (PAPPEL)
Observational
  • Puberté précoce
Hospices Civils de Lyon (Voir sur ClinicalTrials)
juin 2024
juin 2028
05 avril 2025
The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact. Due to a lack of studies and additional data, the reasons for this development are difficult to understand. Among current hypotheses, the entanglement with the evolution of our environment is at the forefront: the action of environmental endocrine disruptors and nutritional factors could play a role in the process of early appearance of pubertal signs. The establishment of a national observatory for early and advanced puberty in collaboration with pediatric endocrinologists (on the front line) would allow a reliable and precise field approach, capable of supplementing epidemiological data, which are currently insufficient. The investigators hypothesize that the establishment of an observatory of pubertal advances (early puberty and advanced puberty) in private medicine is possible, with inclusion of at least 75% of eligible patients, and collection of at least 80% of data.
 Voir le détail

Etablissements

Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données
Clinique du Val d'Ouest - 69130 - Ecully - Auvergne-Rhône-Alpes - France Mélanie Daval Cote, MD En recrutement Contact (sur clinicalTrials)
Clinique rive gauche - 31300 - Toulouse - Occitanie - France Adelaïde DURAND, MD Recrutement non commencé Contact (sur clinicalTrials)
Clinique Saint jean - 34430 - Saint Jean de Vedas - France Active, sans recrutement Contact (sur clinicalTrials)
Hôpital Femme Mère Enfant, Hospices civils de Lyon - 69677 - Bron - France Emilie Doye, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 06000 - Nice - France Frédérique GASTAUD, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 13008 - Marseille - France Active, sans recrutement Contact (sur clinicalTrials)
Pediatric practice - 13012 - Marseille - France Catherine BRUE FABRE En recrutement Contact (sur clinicalTrials)
Pediatric practice - 13090 - Aix-en-Provence - France Céline CASTAINGS-CARLIOZ, MD En recrutement Contact (sur clinicalTrials)
Pediatric Practice - 33600 - Pessac - Nouvelle-Aquitaine - France Olivier PUEL, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 35200 - Rennes - Bretagne - France Livie CHATELAIS, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 37170 - Chambray-lès-Tours - Centre-Val De Loire - France Caroline HASSELMAN, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 37230 - Fondettes - Indre-et-Loire - France Myriam BOUILLO, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 44600 - Saint-Nazaire - Pays De La Loire - France Isabelle GUEMAS, MD Recrutement non commencé Contact (sur clinicalTrials)
Pediatric practice - 49800 - Trélazé - France Julie CHEIGNON, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 54270 - Essey-lès-Nancy - Grand Est - France Julie AUGER, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 64000 - Pau - Nouvelle-Aquitaine - France Catie CESSANS, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 69006 - Lyon - Auvergne-Rhône-Alpes - France Prisca DEALBERTI, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 75010 - Paris - Île-De-France - France Capucine VIGNON SAVOYE, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 75011 - Paris - Île-De-France - France Isabelle FLECHTNER, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 75017 - Paris - Île-De-France - France Maxime GERARD, MD En recrutement Contact (sur clinicalTrials)
Pediatric practice - 75116 - Paris - Ile-de-France - France Active, sans recrutement Contact (sur clinicalTrials)
Pediatric practice - 92300 - Levallois-Perret - Hauts-de-Seine - France Active, sans recrutement Contact (sur clinicalTrials)
Polyclinique Bordeaux rive droite - 33310 - Lormont - Nouvelle-Aquitaine - France Active, sans recrutement Contact (sur clinicalTrials)

Critères

Tous
Inclusion Criteria:

Precocious puberty group (PP) :

- Suspected precocious puberty (girl aged < 8 years or boy aged < 9 years when the
first signs of development* appear)

- Suspected precocious puberty (girl aged < 8 years or boy aged < 9 years when the
first signs of development* appear)

Advanced puberty group (AP) :

- Suspected advanced puberty (girl aged ≥ 8 and < 10 years or boy aged ≥ 9 and < 11
years when the first signs of development* appear)

- First consultation with the investigator (pediatric endocrinologist).

Control group :

- Boy or girl without signs of pubertal development (Tanner 1);

- Matched to the PP group on sex and age (+/- 1 year);

- Consultation with the same investigator over the same period (same quarter) as a
patient in the PP group


All groups

- Consultation with the same investigator over the same period (same quarter) as a
patient in the PP group

- Family not speaking French, language barrier.