Informations générales (source: ClinicalTrials.gov)
PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly (PROMETHEE)
Interventional
Phase 4
Groupe Francais De Pneumo-Cancerologie (Voir sur ClinicalTrials)
septembre 2024
août 2028
18 octobre 2024
The objective of the study is to prospectively generate real-life data in patients aged
≥70 years treated in first line for a thoracic tumor (Non-Small-Cell Lung Carcinoma)
according to best standard of care as defined by the European Society for Medical
Oncology (ESMO). This cohort will aim to:
- characterize participants in terms of geriatrics, biology and carcinology
- describe the treatment modalities by stage, as well as the results in terms of
efficacy, safety and impact on quality of life.
At the same time, exploratory sub-cohorts will be identified including participants
treated uniformly with the same molecule, and/or the same innovative strategy.
Participants will be followed in accordance with investigator's usual clinical practice
at the corresponding site. They will be asked to:
- visit the clinic as per physician's request for checkups and tests for assessing
general condition and clinical efficacy and tolerance of current treatment.
- perform the necessary regular para-clinical examinations (lab testing, imaging,
re-biopsy).
- provide blood samples for bio-bank repository
- perform assessments specific to older adults
- answer three quality of life questionnaires
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHI DE CRETEIL | Isabelle MONNET | 24/03/2025 14:02:16 | Contacter | ||
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| AP-HP - Hôpital Cochin | Marie WISLEZ | Contact (sur clinicalTrials) | |||
| AP-HP - Hôpital Tenon | Constance METEYE | Contact (sur clinicalTrials) | |||
| CH DE VERSAILLES SITE ANDRE MIGNOT | Cécile DUJON | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Cantre Catalan d Oncologie - 66000 - Perpignan - France | Sabine VIEILLOT | Contact (sur clinicalTrials) | |||
| Centre d Oncologie de Gentilly - 54000 - Nancy - France | Laurene GAVOILLE | Contact (sur clinicalTrials) | |||
| Centre Léon Bérard - 69373 - Lyon - France | Chantal DECROISETTE | Contact (sur clinicalTrials) | |||
| CH Annecy Genevois - 74374 - Pringy - France | Emilie PLUQUET | Contact (sur clinicalTrials) | |||
| CH Bastia - 20600 - Bastia - France | Pascal THOMAS | Contact (sur clinicalTrials) | |||
| CH du Pays d Aix - 13616 - Aix En Provence - France | Stéphanie MARTINEZ | Contact (sur clinicalTrials) | |||
| CH Elbeuf - 76503 - Elbeuf - France | Pierre Alexandre HAUSS | Contact (sur clinicalTrials) | |||
| CH La Rochelle - 17000 - La Rochelle - France | Marion LAFARGE | Contact (sur clinicalTrials) | |||
| CH Métropole-Savoie - 73000 - Chambery - France | Julian PINSOLLE | Contact (sur clinicalTrials) | |||
| CHD Les Oudairies - 85000 - La Roche Sur Yon - France | Acya BIZIEUX | Contact (sur clinicalTrials) | |||
| CHITS Toulon Sainte Musse - 83056 - Toulon - France | Clarisse AUDIGIER VALETTE | Contact (sur clinicalTrials) | |||
| CHU de la Réunion - 97410 - Saint-pierre - France | Eric HUCHOT | Contact (sur clinicalTrials) | |||
| CHU Dupuytren - 87042 - Limoges - France | Yannick SIMONNEAU | Contact (sur clinicalTrials) | |||
| CHU Hôpital Montpied - 63000 - Clermont-ferrand - France | Patrick MERLE | Contact (sur clinicalTrials) | |||
| CHU Hôpital Ponchailloux - 35033 - Rennes - France | Charles RICORDEL | Contact (sur clinicalTrials) | |||
| CLCC Paul Strauss - 67000 - Strasbourg - France | Roland SCHOTT | Contact (sur clinicalTrials) | |||
| Clinique Mutualiste - 44600 - Saint Nazaire - France | Thierry CHATELLIER | Contact (sur clinicalTrials) | |||
| GHEF Site de Meaux - 77100 - Meaux - France | Chrystèle LOCHER | Contact (sur clinicalTrials) | |||
| Hôpital d'Instruction des Armées Saint-Anne - 83041 - Toulon - France | Olivier BYLICKI | Contact (sur clinicalTrials) | |||
| Hôpital Henri Duffaut - 84000 - Avignon - France | Nicolas CLOAREC | Contact (sur clinicalTrials) | |||
| Hôpital Nord OUest - 69655 - Villefranche Sur Saone - France | Lionel FALCHERO | Contact (sur clinicalTrials) | |||
| Hôpital Robert Boulin - 33505 - Libourne - France | Samir ABDICHE | Contact (sur clinicalTrials) | |||
| Oncologie CHBA - 56000 - Vannes - France | Gonzague DE CHABOT | Contact (sur clinicalTrials) | |||
| Oncologie Thoracique Hôpital Morvan - 29200 - Brest - France | Renaud DESCOURT | Contact (sur clinicalTrials) | |||
| Oncologie Thoracique Hôpital Nord - 13915 - Marseille - France | Laurent GREILLIER | Contact (sur clinicalTrials) | |||
| Pneumologie Centre François Baclesse - 14000 - Caen - France | Hubert CURCIO | Contact (sur clinicalTrials) | |||
| Pneumologie CHI Quimper - 29000 - Quimper - France | Romain CORRE | Contact (sur clinicalTrials) | |||
| Pneumologie CHR - 45067 - Orleans - France | Hugues MOREL | Contact (sur clinicalTrials) | |||
| Pneumologie CHU Felix Guyon - 97400 - Saint Denis - France | Diane MOREAU | Contact (sur clinicalTrials) | |||
| Pneumologie CHU St Etienne - 42270 - Saint-etienne - France | Sophie BAYLE-BLEUEZ | Contact (sur clinicalTrials) | |||
| Pneumologie Hôpital Charles Nicolle - 76031 - Rouen - France | Florian GUISIER | Contact (sur clinicalTrials) | |||
| Pneumologie Hospices Civils de Colmar - 68024 - Colmar - France | Lionel MOREAU | Contact (sur clinicalTrials) | |||
| Polyclinique de Blois - 41260 - La Chaussee Saint Victor - France | Philippe LAPLAIGE | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Patient ≥70 years
- Non-small-cell lung cancer for which the multidisciplinary consultation required
systemic treatment regardless of Tumor-Node-Metastasis (TNM) stage
- Patient naïve to systemic anticancer treatment for bronchial neoplasia
- Patient covered by social security
- Patient eligible for systemic treatment
- Systemic treatment with marketing authorization in the indication, available in
routine care early access or compassionate access.
- Patient able to understand the protocol
- Patient not opposed to the collection of data concerning him/her
- Signature of study consent form.
- Patient ≥70 years
- Non-small-cell lung cancer for which the multidisciplinary consultation required
systemic treatment regardless of Tumor-Node-Metastasis (TNM) stage
- Patient naïve to systemic anticancer treatment for bronchial neoplasia
- Patient covered by social security
- Patient eligible for systemic treatment
- Systemic treatment with marketing authorization in the indication, available in
routine care early access or compassionate access.
- Patient able to understand the protocol
- Patient not opposed to the collection of data concerning him/her
- Signature of study consent form.
- Patients under guardians or curators
- Patient not under the care of the investigating center and not monitored by the
investigating center
- Patient already treated with systemic therapy for NSCLC