Informations générales (source: ClinicalTrials.gov)
Evolution of Ocular Growth in Myopic Children: A Prospective Cohort Study (PREMYOM1000)
Observational
Fondation Ophtalmologique Adolphe de Rothschild (Voir sur ClinicalTrials)
avril 2025
avril 2033
13 mai 2025
Myopia and high myopia are the leading causes of visual impairment and blindness
worldwide. The total number of myopic people globally was estimated to be 2.6 billion in
2020, and it could reach 4.8 billion by 2050 unless preventive interventions are
implemented.
Strategies to slow the progression of myopia, such as contact lenses, orthokeratology,
atropine, and increased time spent outdoors, have shown promising results, although
evidence varies depending on the method. However, most research has been conducted in
Asia, and there are few studies on ocular growth in myopic children in Europe. Meanwhile,
the prevalence of myopia is also increasing significantly in Europe, particularly in
France.
Understanding the growth of the myopic eye in European children is crucial. Cohort
studies of myopic children are scarce and do not always include high-quality imaging. A
cohort of myopic children with prospective collection of the best retinal and corneal
images, along with ophthalmological exams to detail and model the growth of the myopic
eye, will provide valuable insights to enhance our understanding of ocular growth and its
inter-individual variability.
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| HOPITAL FONDATION A. DE ROTHSCHILD | Sophie Bonnin | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Myopia in at least one eye, defined as a refractive error in spherical equivalent ≤
-0.50 diopters (autorefraction under cycloplegia)
- Affiliated or beneficiary of a social security system
- Explicit consent from a holder of parental authority
- Myopia in at least one eye, defined as a refractive error in spherical equivalent ≤
-0.50 diopters (autorefraction under cycloplegia)
- Affiliated or beneficiary of a social security system
- Explicit consent from a holder of parental authority
- Presence of trauma in both eyes
- Presence of inflammatory conditions in both eyes
- History of intraocular surgery (cataract, filtering surgery, intra-vitreal surgery)
in both eyes
- Patient benefiting from legal protection measures