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440000271
8610Z
Centre Hospitalier Régional (C.H.R.)
44

Adresse

  1 PL ALEXIS RICORDEAU 44093 NANTES CEDEX 1   Accès au plan

Listes des essais cliniques en recrutement

Etude Statut Dernière mise à jour
NCT03976180 A Multicentre, Prospective, Randomized, Multi-arm, Multi-stage Clinical Trial of High-flow Oxygen for Vaso-occlusive Pain Crisis in Adult Patients With Sickle Cell Disease; En recrutement 13 décembre 2025
NCT03970577 Rituximab From the First Episode of Minimal Change Nephrotic Syndrome for Preventing Relapse Risk in Adult Patients: a Multicenter Randomized Controlled Trial En recrutement 13 décembre 2025
NCT04292080 Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophy En recrutement 13 décembre 2025
NCT04220931 Intrapapillary Botulinum Toxin Injection for PREvention of Post-surgical PAncREactic Fistula En recrutement 13 décembre 2025
NCT03655145 Randomized Prospective Phase III Clinical Trial Comparing HLA 10/10 Matched Unrelated Donor and Haploidentical Allogenic Hematopoietic Stem Cell Transplantation After Myeloablative Conditioning Regimen En recrutement 13 décembre 2025
NCT04116502 A Phase III, Randomised, Open-label, Multicenter International Trial Comparing Ruxolitinib With Either HydRoxycarbamIDe or Interferon Alpha as First Line ThErapy for High Risk Polycythemia Vera En recrutement 13 décembre 2025
NCT03483246 Impact of Fecal Microbiota Transplantation in Ulcerative Colitis: a Randomized, Sham Controlled Trial En recrutement 13 décembre 2025
NCT03976063 Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation: a Double-blinded Randomized Controlled Trial En recrutement 13 décembre 2025
NCT04564001 Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocilizumab in Refractory or Relapsing Takayasu Arteritis En recrutement 13 décembre 2025
NCT03250546 Randomized Prospective Phase II Clinical Trial Using Post-Transplantation Cyclophosphamide for Prevention of GVHD in Haploidentical and HLA-9/10 Mismatched Unrelated Donors Hematopoietic Stem Cell Transplant En recrutement 13 décembre 2025
NCT03770663 Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease : Multicentric Randomized Phase III Trial En recrutement 13 décembre 2025
NCT03236129 Allogeneic Immunotherapy for Hematological Malignancies by Selective Depletion of Regulatory T Cells: A Confirmatory, Randomized, Double Blinded Trial En recrutement 13 décembre 2025
NCT02905734 Nicotine Replacement Therapy in Nicotine-dependent Arrestees: a Monocentric Randomized Simple Blind Study En recrutement 13 décembre 2025
NCT03664427 Pharmacogenetics of Veno-Occlusive Disease (VOD) in Children With Haematological Stem Cell Transplantation (HSCT) En recrutement 13 décembre 2025
NCT02782039 Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE) En recrutement 13 décembre 2025
NCT02450396 Prospective Observational Study About Pregnancy and Medically Assisted Conception in Rare Diseases En recrutement 13 décembre 2025
NCT02828202 Constitution of a National Cohort of Patients With Metastatic Melanoma Resectable Stage II or Stage III or IV or Unresectable Primary With the Objective of Setting up Epidemiological Monitoring and Clinico-biological Database, MELBASE En recrutement 13 décembre 2025
NCT03887156 Evaluation of a Donor Testing Kit for the Prediction of Acute GVHD in Patient Receiving a Peripheral Blood Stem Cells Allograft- Predictor 2 En recrutement 13 décembre 2025
NCT04286360 Hematological Anomalies in Children With Rasopathy En recrutement 13 décembre 2025
NCT03976011 Validation and Optimization Methods for a Quantitative Characterization of Motion Abnormalities of the Larynx With Echography En recrutement 13 décembre 2025
NCT04021485 5-year Follow-up of the BETADOSE Trial: Non-inferiority of a 50% Dose Reduction of Antenatal Betamethasone Therapy on the Neurodevelopment of Children Born Before 32 Weeks of Gestation. En recrutement 13 décembre 2025
NCT06311006 Safety Registry of a Fecal Microbiota Transplant Cohort (COSMIC-FMT) En recrutement 13 décembre 2025
NCT06424392 Respiratory and Psychological Impact of Elective Surgery of Congenital Lung Malformations En recrutement 13 décembre 2025
NCT07119606 Multicenter Study of Patients With SHANK3 Mutations: Identification of Genes Modificators in Phelan-McDermid Syndrome (EUQ13) En recrutement 13 décembre 2025
NCT06561854 Free Regimen of Dexamethasone as Initial Therapy for Advanced Relapsed/Refractory Multiple Myeloma: an Open-label Randomized, Non-inferiority, Controlled Trial En recrutement 13 décembre 2025
NCT05327894 Interfant-21 International Collaborative Treatment Protocol for Infants Under One Year With KMT2A-rearranged Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia. En recrutement 13 décembre 2025
NCT06471556 Efficacy of Methylprednisolone Pulses in Neuroendocrine Celles Hyperplasia of Infancy : An Early Phase Study En recrutement 13 décembre 2025
NCT06055699 Association Between the Occurrence of a Clinical RElapse and Gut MIcrobiota Modifications: a Cohort Study of Patients With pSOriasis En recrutement 13 décembre 2025
NCT06421012 Preoxygenation for Tracheal Aspirations in Intensive Care, a Randomized Controlled Trial En recrutement 13 décembre 2025
NCT05878782 Occupational Engagement in Alder Adults With Cancer - the Impact of Occupational Therapy (OCEAN-OT): a Multicenter Randomized Controlled Trial En recrutement 13 décembre 2025
NCT06256705 Multi-modal Characterisation of Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort En recrutement 13 décembre 2025
NCT06334965 Multi-modal Characterisation of Hepatocellular Carcinoma (HCC) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort En recrutement 13 décembre 2025
NCT06083129 Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor Following a Reduced Intensity Conditioning Regimen by Fludarabine-treosulfan En recrutement 13 décembre 2025
NCT06289348 Announcement of Rare Metabolic Diseases as Part of Systematic New-born Screening: the Experience of Phenylketonuria. En recrutement 13 décembre 2025
NCT06235398 Upfront Related Donor Transplantation in Patients With Myelodisplatic Syndrome : a Phase 2 Trial En recrutement 13 décembre 2025
NCT05903365 Etude Observationnelle de Suivi Des Greffes Haplo-identique Dans la Maladie de Fanconi En recrutement 13 décembre 2025
NCT06244862 JAK Inhibitor in Acquired Hemophagocytic synDrome in the Intensive Care Unit En recrutement 13 décembre 2025
NCT06651203 Evaluation of the KIR3DL2 Marker in Flow Cytometry for Sézary Syndrome Diagnosis, Therapeutic Response and Residual Disease: a Prospective and Multicenter Study En recrutement 13 décembre 2025
NCT05532813 Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease). A Phase III, Prospective, Multicentre, Randomized, Double-blind Controlled Study En recrutement 13 décembre 2025
NCT06536166 Blocking Interferon-γ by Ruxolitinib for Treating Inclusion Body Myositis: a Phase IIb Trial En recrutement 13 décembre 2025
NCT05992857 Randomized Controlled Trial Comparing Pancreaticoduodenectomies With or Without Complete Arterial Coverage by Omentoplasty in Patients With High Risk of Postoperative Pancreatic Fistula. En recrutement 13 décembre 2025
NCT06443606 Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy: a 12-month, Double-blind, Randomized, Placebo-controlled Trial With a 12-month, Double-blind, Placebo-free Extension Phase. En recrutement 13 décembre 2025
NCT06147414 Evaluation of the Diagnostic Performance of Non-Invasive Prenatal Diagnosis for Single Gene Disorders En recrutement 13 décembre 2025
NCT06457386 Echocardiography Versus no Echocardiography in Individuals With Staphylococcus Aureus Bacteremia and a VIRSTA Score <3: a Non-inferiority Randomized Controlled Trial En recrutement 13 décembre 2025
NCT06499324 Surgical Treatment of Large Incisional Hernia with Botulinum Toxin a Injection: a Double-blind Randomized Controlled Trial En recrutement 13 décembre 2025
NCT06334497 Letermovir/Valganciclovir Combination Versus Valganciclovir Monotherapy for Treatment of Cytomegalovirus (CMV) Infections in Kidney Transplant Recipients En recrutement 13 décembre 2025
NCT05117398 Randomized Open-label Controlled Trial Evaluating a Single-dose Intravenous Dalbavancin Versus Standard Antibiotic Therapy During Catheter-related Bloodstream Infections Due to Staphylococcus Aureus En recrutement 13 décembre 2025
NCT05772559 Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies - ALARM3 En recrutement 13 décembre 2025
NCT04307576 ALLTogether1 - A Treatment Study Protocol of the ALLTogether Consortium for Children and Young Adults (0-45 Years of Age) With Newly Diagnosed Acute Lymphoblastic Leukaemia (ALL) En recrutement 13 décembre 2025
NCT05866991 Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders En recrutement 13 décembre 2025
NCT05162508 Characterization of the Impact of SARS-CoV-2 Variability on the Course of COVID-19 in Patients With Severe Disease Hospitalized in Intensive Care Units: Prospective Observational Multicentric Study En recrutement 13 décembre 2025
NCT06057597 Randomized Controlled Non-inferiority Trial Evaluating the Safety and Efficacy of the Omega Gastric Bypass With 150 cm Biliopancreatic Loop Length Compared to the Roux-en-Y Gastric Bypass En recrutement 13 décembre 2025
NCT05488288 Bariatric Surgery With Mesh Repair of Ventral Hernia: a Randomized Controlled Trial En recrutement 13 décembre 2025
NCT05521776 Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity : a Multicenter Randomized Trial En recrutement 13 décembre 2025
NCT05946564 A Multicenter Randomized Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO En recrutement 13 décembre 2025
NCT06464146 Pain Reduction for Limb Injuries in Pediatric Emergency Departments: A Randomised Clinical Trial Comparing Intranasal Fentanyl or Intranasal Ketamine to Oral Morphine En recrutement 13 décembre 2025
NCT06181695 Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric Emergency Department: a Double Blind Randomized Versus Placebo Controlled Trial En recrutement 13 décembre 2025
NCT06258915 Randomized Controlled Multicenter Study Comparing Efficacy and Safety of Adalimumab to That of Mycophenolate Mofetil in Steroid Dependent Non-infectious Uveitis En recrutement 13 décembre 2025
NCT05440331 Morbidity and Mortality in Operating Room: Surgery and Standardized Communication En recrutement 13 décembre 2025
NCT06076317 Randomized Multicenter Clinical Trial of the Efficacy of a Telemedicine Monitoring in the Management of a Depressive Episode After an Hospitalisation in Medicine or Surgery En recrutement 13 décembre 2025
NCT06860269 A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia En recrutement 13 décembre 2025
NCT05256693 Prevention of C.Difficile Infections With Oral Vancomycine in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant: a Double-blind Placebo-controlled Randomized Clinical Trial En recrutement 13 décembre 2025
NCT05338190 A Phase 3 Randomized and Double-blind Controlled Trial Comparing the Efficacy and Safety of Subcutaneous Belimumab or Placebo in Addition to Rituximab in Adult Patients With Persistent or Chronic Immune Thrombocytopenia (ITP) En recrutement 13 décembre 2025
NCT05041023 Experience of Relatives and Caregivers of Death in ICU After the Withdrawal of Life-sustaining Therapies, Associated With an Organ Procurement Procedure (Controlled Donation After Circulatory Death). En recrutement 13 décembre 2025
NCT05378815 Platelet-rich Plasma in Symptomatic Knee Osteoarthritis: a Randomized, Double-blind, Placebo-controlled, Multicentre Trial En recrutement 13 décembre 2025
NCT04822766 Allogeneic Hematopoietic Cell Transplantation Versus Best Available Standard of Care Therapy in Elderly Patients With Acute Myeloid Leukemia: a Randomized Phase 3 Trial En recrutement 13 décembre 2025
NCT05126186 Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide for Rescuing Patients With Graft Failure: a Phase II Study En recrutement 13 décembre 2025
NCT05205902 TOtal Skin Electron Beam Therapy (Low-dose) for Tumor Clone Eradication in Early-stage Mycosis Fungoides: a Prospective Randomized Controlled Study En recrutement 13 décembre 2025
NCT05559827 Randomized Prospective Trial Evaluating the Efficacy of the antiCD38 Monoclonal Antibody Isatuximab in the Treatment of PCRA by Major ABO Mismatch After Allogeneic Hematopoietic Stem Cell Transplantation En recrutement 13 décembre 2025
NCT05952674 Resistant Depression and Vagus Nerve Stimulation : a Medico-economic, Multicenter, Randomized and Open Trial En recrutement 13 décembre 2025
NCT04702256 Induction Therapy for Lupus Nephritis With no Added Oral Steroids: An Open Label Randomised Multicentre Controlled Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF En recrutement 13 décembre 2025
NCT04871191 Salvage Therapy for Patients with Inadequate Response to Standard of Care Therapy in Granulomatosis with Polyangiitis En recrutement 13 décembre 2025
NCT05597540 Efficacy of 7 Days Versus 14 Days of Antibiotic Therapy for Acute Pyelonephritis in Kidney Transplant Recipients, a Multicentre Randomized Non-inferiority Trial. En recrutement 13 décembre 2025
NCT04404387 A Multicentre Concealed-Allocation Parallel-Group Blinded Randomized Controlled Trial to Ascertain the Effect of High-Dose Intravenous Vitamin C Compared to Placebo on Mortality or Persistent Organ Dysfunction at 28 Days in Septic Intensive Care Unit Patients En recrutement 13 décembre 2025
NCT04968899 Intravenous Immunoglobulin Plus Oral Prednisone or High-dose Dexamethasone, for Adults With Immune Thrombocytopenia (ITP) With Moderate and Severe Bleeding: a Randomized, Multicentre Trial En recrutement 13 décembre 2025
NCT05124977 Antimicrobial Stewardship For Ventilator Associated Pneumonia in Intensive Care En recrutement 13 décembre 2025
NCT05874505 "Multicenter, Randomized, Prospective Trial Comparing the Efficacy and Safety of Adalimumab to That of Tocilizumab in Severe Uveitis of Behçet's Disease" (UVB) : Treatment of UVeitis in Behçet's Diseases With Biologics En recrutement 13 décembre 2025
NCT05126849 Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide in Patients With Acquired Refractory Aplastic Anemia or in Relapse After Immunosuppression: a Nationwide Phase II Study En recrutement 13 décembre 2025
NCT04280497 A Multicentre Concealed-Allocation Multi-arms Blinded Randomized Controlled Trial to Identify the Best Sepsis Population for Corticotherapy En recrutement 13 décembre 2025
NCT04997733 Fecal Microbiota Transplantation in Crohn's Disease as Relay After Anti-TNF Withdrawal En recrutement 13 décembre 2025
NCT04554108 Acute Non-severe Osteomyelitis in Children - Outpatient Management Strategy With Oral Antibiotic Therapy Compared to a Standard Strategy With Conventional Hospitalization and Intravenous Antibiotic Therapy: a Randomized Open-label Non-inferiority Study With Bayesian and Medical-economic Analyses. En recrutement 13 décembre 2025
NCT04155086 "Fetal Aneuploidy Screening (21, 18 and 13) by Analysis of Circulating Fetal DNA in a Population of Pregnant Patients With Autoimmune Diseases" En recrutement 13 décembre 2025
NCT05672550 Dose-adjustment of Enoxaparin by a Bayesian Pharmacological Approach in Pediatric Kidney Transplant Recipients En recrutement 13 décembre 2025
NCT04972760 Baricitinib in Patients With Relapsing or naïve Dermatomyositis: a Multicenter Randomized Controlled Trial (BIRD) En recrutement 13 décembre 2025
NCT04776473 Open Versus Closed Treatment of Intra-articular Fractures of the Mandibular Condyle: a Multicentre Randomized Controlled Trial En recrutement 13 décembre 2025
NCT04292054 "Antibioprophylaxis for Excision-graft Surgery in Burn Patient: a Multicenter Randomized Double-blind Study: A2B Trial" En recrutement 13 décembre 2025
NCT03768271 French Cohort on the Becoming of Recent Articular Psoriatic Rheumatism (A Psoriatic Arthritis CoHort) En recrutement 13 décembre 2025
NCT06536166 Blocking Interferon-γ by Ruxolitinib for Treating Inclusion Body Myositis: a Phase IIb Trial En recrutement 01 novembre 2025
NCT04972760 Baricitinib in Patients With Relapsing or naïve Dermatomyositis: a Multicenter Randomized Controlled Trial (BIRD) En recrutement 25 octobre 2025
NCT03655145 Randomized Prospective Phase III Clinical Trial Comparing HLA 10/10 Matched Unrelated Donor and Haploidentical Allogenic Hematopoietic Stem Cell Transplantation After Myeloablative Conditioning Regimen En recrutement 25 octobre 2025
NCT05028348 A Phase 3 Randomized, Open-label Trial of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM) Active, sans recrutement 29 octobre 2024
NCT05443087 Dosing of Various Multi Kinases Inhibitors Plasma Concentrations for Patients Treated for Their Advanced Digestive Cancer, With the Aim to Determine the Best Optimal Dose for Each Treatment, in the Future En recrutement 02 mars 2024
NCT04282473 Peristomal Hernia Rate 5 Years After a Terminal Colostomy With the Parietex ™ TCM Parietal Prosthesis Versus Without Mesh: Material-epidemiology Study En recrutement 20 mars 2023
NCT04222283 Switch to Tenofovir Alafenamide (TAF), Emtricitabine (FTC), Bictegravir (BIC)(Biktarvy®) in HIV-1-infected Patients Over 65 Years Old at Risk of Polymedication Statut inconnu 20 mars 2023
NCT04183608 An Open-label Randomized Trial COmparing staNdard of Care Versus Treat to Target With telemonitoRing and Patient Education in Patients With Ulcerative cOlitis Initiating adaLimumab: The CONTROL Trial En recrutement 20 mars 2023
NCT03235310 ANRS CO1 EPF Prospective Observational Cohort Study on Mother-to-child Transmission HIV1 and/or HIV2 and Prevention Statut inconnu 20 mars 2023
NCT03084783 Dexamethasone in Herpes Simplex Virus Encephalitis Open Label Randomized Controlled Trial With an Observer-blinded Evaluation at 6 Months Statut inconnu 20 mars 2023
NCT02898987 Dataids Prospective Observational Cohort on Quality of Care of French HIV Infected Patients En recrutement 20 mars 2023
NCT02381574 French Lumbar Total Disk Replacement Observational Study (FLTDR Observational Study) Statut inconnu 20 mars 2023
NCT01066689 Phase III Study of Impact of Treatment With Rituximab on the Progression of Humoral Acute Rejection After Renal Transplantation. Statut inconnu 20 mars 2023
NCT04328298 French Register Of Patients With Hemopathy Eligible For CAR-T Cell Treatment (DESCAR-T) En recrutement 20 mars 2023
NCT03764150 Factors Associated With Hypoventilation in the Myotonic Dystrophy, Progressive Profile Over 5 Years Complet 20 mars 2023
NCT02526095 National Oesophageal and Gastric Carcinomas Data Base Construction: the FREGAT (French EsoGastric Tumours) Data Base En recrutement 20 mars 2023
NCT02416388 Phase II/III Randomized Study to Improve Overall Survival in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus Mycophenolate Mofetil Prophylaxis of Graft Versus Host Disease in Allografted Patients in First CR : a Backbone InterGroup-1 Trial En recrutement 20 mars 2023
NCT04172480 HUSH Restriction in HIV Infected Patients Statut inconnu 05 novembre 2022
NCT03795376 HIV Prevention in France : "Dat'AIDS Prevention" En recrutement 05 novembre 2022
NCT03750994 Economic Evaluation of Innovative Molecular Analyses in Onco-haematology (PRME-K 2016) Statut inconnu 05 novembre 2022
NCT02938858 The French Registry on the First-line Treatment of Non High-risk Acute Promyelocytic Leukemia (APL) in Patients Aged ≤ 70 Years Active, sans recrutement 05 novembre 2022
NCT02701608 Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Staphylococcus (Relais Oral Dans le Traitement Des Endocardites à Staphylocoques Multi-sensibles) Statut inconnu 05 novembre 2022
NCT02701595 Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus (Relais Oral Dans le Traitement Des Endocardites à Streptocoques Multi-sensibles) Statut inconnu 05 novembre 2022
NCT00444652 Thromboprophylaxis During Bariatric Surgery Statut inconnu 29 octobre 2022
NCT00443339 A Phase II Study of Darbepoetin Alpha in Myelodysplastic Syndromes (MSD) Statut inconnu 29 octobre 2022
NCT00424229 Phase II Study of the Efficacy and Safety of Lenalidomide in Adult Subjects With Intermediate-2-or Higt Risk Myelodysplastic Syndrome(MDS) Associated With a Deletion (DEL) 5q [31] Statut inconnu 29 octobre 2022