NCT Etude Statut Mise à jour
NCT03875755 Reduction of Insulin Therapy Under Myo-inositol for the Treatment of Gestational Diabetes Mellitus: a Randomized Multicenter and Prospective Trial. MYO-GDM Study En recrutement 25 octobre 2025
NCT03976063 Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation: a Double-blinded Randomized Controlled Trial En recrutement 25 octobre 2025
NCT04184635 Assessment of ECMO in Acute Myocardial Infarction With Non-reversible Cardiogenic Shock to Halt Organ Failure and Reduce Mortality (ANCHOR) En recrutement 25 octobre 2025
NCT02905734 Nicotine Replacement Therapy in Nicotine-dependent Arrestees: a Monocentric Randomized Simple Blind Study En recrutement 25 octobre 2025
NCT02450396 Prospective Observational Study About Pregnancy and Medically Assisted Conception in Rare Diseases En recrutement 25 octobre 2025
NCT06518694 Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction En recrutement 25 octobre 2025
NCT06461065 Evaluation of Neurodevelopmental Trajectories in Children According to the Glycemic Profile Associated With Different Early Treatment Modalities in Children With Type 1 Diabetes (T1DM) En recrutement 25 octobre 2025
NCT05764057 DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction En recrutement 25 octobre 2025
NCT06057597 Randomized Controlled Non-inferiority Trial Evaluating the Safety and Efficacy of the Omega Gastric Bypass With 150 cm Biliopancreatic Loop Length Compared to the Roux-en-Y Gastric Bypass En recrutement 25 octobre 2025
NCT05488288 Bariatric Surgery With Mesh Repair of Ventral Hernia: a Randomized Controlled Trial En recrutement 25 octobre 2025
NCT05387954 Transcatheter Patent Foramen Ovale (PFO) Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Between 60 and 80 Years Old : a Randomised Controlled Trial. En recrutement 25 octobre 2025
NCT05565222 Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit En recrutement 25 octobre 2025
NCT06860269 A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia En recrutement 25 octobre 2025
NCT04961528 ACid Tranexamic or Terlipressin for Initial Emergency Treatment of Mild to seVere hEmoptysis: a Randomized Trial. En recrutement 25 octobre 2025
NCT05216731 Bypass Versus Endovascular Procedure in Long Lesions of the Superficial Femoral Artery in the Claudicant En recrutement 25 octobre 2025
NCT05247554 Randomized Controlled Trial Testing the Effect of Hydroxychloroquine Combined With Low-dose Corticosteroid Therapy in Pulmonary Sarcoidosis En recrutement 25 octobre 2025
NCT04554108 Acute Non-severe Osteomyelitis in Children - Outpatient Management Strategy With Oral Antibiotic Therapy Compared to a Standard Strategy With Conventional Hospitalization and Intravenous Antibiotic Therapy: a Randomized Open-label Non-inferiority Study With Bayesian and Medical-economic Analyses. En recrutement 25 octobre 2025
NCT04763447 Impact of Omalizumab Withdrawal After a 3 Year Duration Treatment in Well Controlled Severe Allergic Asthma : a Multicentric Randomized Controlled Trial En recrutement 25 octobre 2025
NCT05565222 Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit En recrutement 27 septembre 2025
NCT06494293 How Many Patients Suffering Major Trauma Would be Eligible for a Pre-hospital Transfusion: A Multicentre Retrospective Study. En recrutement 18 septembre 2025
NCT04411043 Prospective and Retrospective Study Evaluating Epidemiological, Clinical, Molecular and Therapeutic Data of Prolymphocytic Leukemia T En recrutement 18 septembre 2025
NCT05350826 Targeted Therapies in Chronic Lymphocytic Leukemia and Medico-economic Evaluation of the Ambulatory Medical Assistance Nurse Program : a Prospective Multicenter Randomized Study En recrutement 18 septembre 2025
NCT03663725 Phase III Randomised Trial Evaluating Treatment Intensification With Temozolomide in Adults With a Glioblastoma En recrutement 18 septembre 2025
NCT04638725 Identification of Genetic Determinants for Treatment Resistance/Sensitivity and/or Toxicity in Adjuvant Setting for HER2 Positive Breast Cancer En recrutement 18 septembre 2025
NCT04657783 French National Cohort of People With Type 1 Diabètes: the SFDT1 Study En recrutement 18 septembre 2025
NCT04654923 Epidemiological Survey on Perioperative Hypersensitivity Reactions in France by the GERAP Network (Groupe d'étude Des réactions Anaphylactiques périopératoires) En recrutement 18 septembre 2025
NCT04781790 French National Registry of Bone Marrow Failures: Prospective and Retrospective Database Associated to a Collection of Biological Samples: RIME Project En recrutement 18 septembre 2025
NCT03900221 French Registry for Monitoring Pregnancies and Children of Women With Multiple Sclerosis Within The Observatoire Français de la Sclérose en Plaque (OFSEP) Cohort En recrutement 18 septembre 2025
NCT06031805 a French Observational Prospective Multicenter Study of Adult Patients Treated in the Real-life Setting With Olaparib for the Treatment of Metastatic Castration-resistant Prostate Cancer En recrutement 18 septembre 2025
NCT06293625 Personalising and Refining Neo-adjuvant Chemotherapy in Locally Advanced but Resecable Colon Cancer in the Elderly of 70 Years Old or More Phase III Multicentric Open-label Randomized Controlled Trial En recrutement 18 septembre 2025
NCT03825861 Neoadjuvant FOLFIRINOX in the Treatment of Locally Advanced Gastric Cancer En recrutement 18 septembre 2025
NCT04188145 A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Metastatic Colorectal Cancer En recrutement 18 septembre 2025
NCT04325425 Folfirinox Versus Platinum - Etoposide as First Line Chemotherapy for Metastatic Grade 3 Poorly Differentiated Neuroendocrine Carcinoma of Gastro Entero Pancreatic and Unknown Primary Associated With Molecular Profiling for Therapeutic Targets & Predictive Biomarkers Identification En recrutement 18 septembre 2025
NCT06224764 Assessment of the Impact of the Return Home of Premature Newborns With Intrauterine Growth Retardation Weighing Less Than 2 Kilos (Low Birth Weight) on Short- and Long-term Morbidity/Mortality En recrutement 18 septembre 2025
NCT05961488 Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest En recrutement 18 septembre 2025
NCT03819101 A Phase III Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer En recrutement 18 septembre 2025
NCT06318117 Observational Study on the Use of Infant Formulas Based on Rice Protein Hydrolysate in Real Life Conditions En recrutement 18 septembre 2025
NCT05539391 Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on Postintubation Morbidity: A Cluster Randomized Controlled Trial En recrutement 18 septembre 2025
NCT05299840 Impact of Using the Oncogramme® Device to Select the First Line of Treatment (Chemotherapies +/- Targeted Therapies) for Patients With Metastatic Colorectal Cancer on Progression-free Survival, Treatment Costs, Efficiency and Quality of Life Compared to Usual Patient Care. En recrutement 18 septembre 2025
NCT04664569 National Observatory of Bacterial Meningitis in Children and Newborns En recrutement 18 septembre 2025
NCT02850705 The French Cohort and Biobank of Devic's Neuromyelitis Optica and Related Neurological Disorders (NMOSD) (NOMADMUS) En recrutement 18 septembre 2025
NCT06425367 Impact of Performing a Rapid Antibiotic Susceptibility Test (MHR-SIR) on Antibiotic Therapy Adaptation in Adult Patients with Enterobacterales Bacteremia, Controlled, Randomized Cluster and Cross-over Study En recrutement 18 septembre 2025
NCT06504615 A French, Prospective, Observational, Multicenter Study of Patients Treated With Nivolumab Plus Chemotherapy as First Line Treatment in Advanced or Metastatic Esophageal Squamous Cell Carcinoma, Esophageal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma or Gastric Adenocarcinoma [METAGIO] En recrutement 18 septembre 2025
NCT01522183 An Observational, Non-Interventional, Multi-Center, Multi-National Study of Patients With Atypical Hemolytic-Uremic Syndrome (aHUS Registry) En recrutement 18 septembre 2025
NCT04174807 Prospective Study of Antenatal Diagnostic Criteria for Digestive Complications of Gastroschisis En recrutement 18 septembre 2025
NCT04326218 Immunopathological Analysis in a French National Cohort of Membranous Nephropathy (IHMN) En recrutement 18 septembre 2025
NCT05867225 Onlay Synthetic Bioabsorbable Mesh Herniorrhaphy Versus Herniorrhaphy Only in the Primary Treatment of Large Hiatal Hernia: a Multicenter, Randomized, Parallel-group, Evaluator Blinded, Phase III Clinical Trial En recrutement 18 septembre 2025
NCT06450314 De-escalation of Medical Therapies in HER2-positive Metastatic Breast Cancer in Long-term Persistent Response and Minimal Residual Disease Undetectable in Circulating Tumor DNA En recrutement 18 septembre 2025
NCT06185491 Assessment of HGI (Hemoglobin Glycation Index) Variability Over Time in Patients Living with Diabetes Using Continuous Glucose Monitoring En recrutement 18 septembre 2025
NCT05168839 Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage: a Single-blind Phase III Multicenter Randomized Controlled Trial (Intergroup FRENCH-GRECCAR Trial) En recrutement 18 septembre 2025
NCT05232916 A Randomized, Multicenter, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects With Residual Disease or High-Risk PCR After Both Neoadjuvant and Postoperative Adjuvant Trastuzumab-based Therapy (FLAMINGO-01) En recrutement 18 septembre 2025
NCT06111586 A 52-week Randomized, Double-blind, Placebo-controlled, Multi-center Phase 2b Study With a 52-week Blinded Extension Assessing Safety and Efficacy of Frexalimab, a CD40L-antagonist Monoclonal Antibody, for Preservation of Pancreatic β-cell Function in Adults and Adolescents With Newly Diagnosed Type 1 Diabetes on Insulin Therapy En recrutement 18 septembre 2025
NCT05596786 Evaluation de l'efficacité et de la sécurité du Rituximab Chez Les Patients Avec Une Pneumopathie Interstitielle Diffuse Progressive Avec Composante Inflammatoire : Essai Clinique randomisé Multicentrique en Double Insu Contre Placebo En recrutement 18 septembre 2025
NCT06078384 Adjuvant Pembrolizumab and Chemotherapy or Surveillance in Early Triple Negative breAst Cancer With High Stromal Tumor-infiltrating Lymphocytes (TILs) Score En recrutement 18 septembre 2025
NCT06450990 Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product (BGY-1601-VT) as a First-line Monotherapy in Women With Acute Vaginal Infection: a Randomized, Double-blind, Placebo-controlled Study En recrutement 18 septembre 2025
NCT06679608 Prospective Longitudinal Multicentric Study to Evaluate Syde® Digital Endpoints in Healthy Adults En recrutement 18 septembre 2025
NCT05297617 Single-arm Study to De-escalate Adjuvant Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low Risk of Metastasis En recrutement 18 septembre 2025
NCT04451915 Late Versus Early Management of Gestational Diabetes Mellitus: a Non Inferiority Randomized Multicenter Trial En recrutement 18 septembre 2025
NCT06104566 A Global Multicenter, Open Label, Randomized Phase 3 Registrational Study of Lisaftoclax (APG-2575) in Previously Treated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (GLORA Study) En recrutement 18 septembre 2025
NCT06012006 Determination of the Minimal Clinically Significant Difference (MCID) of Multidimensional Dyspnea Profile (MDP) Scores in Chronic Obstructive Pulmonary Disease (COPD) Patients During Pulmonary Rehabilitation En recrutement 18 septembre 2025
NCT04890028 Detection and Metabolic Characterization in DOPA PET/CT of no Treated Brain Metastases of Lung Cancer, Breast Cancer and Melanoma En recrutement 18 septembre 2025
NCT04870203 Combination of Baricitinib and Anti-TNF vs. Baricitinib in Patients With Rheumatoid Arthritis: a Randomized Controlled Phase III Trial En recrutement 18 septembre 2025
NCT03656081 Therapeutic Efficacy Comparison of a Six-month Treatment by Itraconazole and Nebulised Ambisome® Versus Treatment by Itraconazole Alone in Non- or Mildly- Immunocompromised Patients with Chronic Pulmonary Aspergillosis: a Prospective, Randomized, Single Blind Study, (single Aspergilloma Excluded) En recrutement 18 septembre 2025
NCT04778657 National Exhaustive Cohort of Hereditary Stomatocytoses and Other Channelopathies Affecting the Red Blood Cell En recrutement 18 septembre 2025
NCT06353854 National French Cohort Evaluating Predictive Factors of Resistance to Immunotherapy in Patients With MSI Metastatic Colorectal Cancer En recrutement 18 septembre 2025
NCT01520844 Multicentric Cohort of HIV Patient With Extrem Profil En recrutement 18 septembre 2025
NCT03236987 CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections En recrutement 18 septembre 2025
NCT06834360 A Randomized, Double-blind, Placebo-controlled, Parallel-group, 52-week Phase 3 Trial to Investigate the Efficacy, Safety, and Tolerability of Itepekimab in Adult Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps En recrutement 18 septembre 2025
NCT06152575 A PHASE 3, OPEN-LABEL STUDY OF ELRANATAMAB MONOTHERAPY VERSUS ELOTUZUMAB, POMALIDOMIDE, DEXAMETHASONE (EPd) OR POMALIDOMIDE, BORTEZOMIB, DEXAMETHASONE (PVd) OR CARFILZOMIB, DEXAMETHASONE (Kd) IN PARTICIPANTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA WHO RECEIVED PRIOR ANTI-CD38 DIRECTED THERAPY En recrutement 18 septembre 2025
NCT05139784 BeAT1D: Benign Autoimmunity and Type 1 Diabetes En recrutement 18 septembre 2025
NCT05006859 Wheelchair Positioning and Neuromuscular Diseases Database (Retrospective and Prospective) En recrutement 18 septembre 2025
NCT02889965 The French Multiple Sclerosis Registry En recrutement 18 septembre 2025
NCT05768711 Phase II Study With Safety run-in of Azacitidine (AZA) Combined With Venetoclax (VEN) in Patients With Higher-risk Chronic Myelomonocytic Leukemia (CMML) En recrutement 18 septembre 2025
NCT06268873 A Phase III, Randomised, Double-Blind Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on Chronic Kidney Disease (CKD) Progression in Participants With CKD and High Blood Pressure En recrutement 18 septembre 2025
NCT03116217 Multicentre Validation of a Fetal Urine Peptidome-based Classifier to Predict Post-natal Renal Function in Posterior Urethral Valves En recrutement 18 septembre 2025
NCT06368804 Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With Pseudomonas Aeruginosa in Adults With Bronchiectasis: a Non-inferiority Randomized Controlled Trial. En recrutement 18 septembre 2025
NCT03148964 Multicentric Cohort of HIV-1 (Human Immunodeficiency Virus 1) Primary Infection Cohort ANRS CO6 PRIMO En recrutement 18 septembre 2025
NCT06533436 Clinical and Economic Comparison of 2 Methods of Intubation Tube Fixation in the Intensive Care Unit: Benefits of Intubation Tube Fixation with AnchorFastTM Versus Current Cord Fixation En recrutement 18 septembre 2025
NCT06512610 Validation of the Use of the "ELN 2022" Risk Stratification System in HLA MENAFC Patients Newly Diagnosed With Acute Myeloid Leukemia En recrutement 18 septembre 2025
NCT04777916 A Prospective Non-interventional Study Documenting the Management and Outcomes of Adult Patients With Acute Myeloid Leukemia (AML) En recrutement 18 septembre 2025
NCT05199051 AGORA-1 /ALFA 2100 Study : a Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults with FLT3-ITD Relapse/refractory (R/R) AML En recrutement 18 septembre 2025
NCT05002556 AFU Registry of the Therapeutic Management and Follow-up of Non-Muscle-Invasive Bladder Cancer En recrutement 18 septembre 2025
NCT06551350 Retrospective Assessment of Referral of a Major Trauma Patient in Val-d'Oise En recrutement 14 février 2025
NCT05625087 A ctDNA Screening Program in Patients With HR+, HER2- Metastatic Breast Cancer for Detection of High-risk Relapse Patients on Any CDK4/6 Inhibitor and a Randomised Phase II Study Comparing Alpelisib Combined With Fulvestrant to Ribociclib Combined With Fulvestrant, in Patients With Persistent Targetable PIK3CA Mutations En recrutement 14 février 2025
NCT05618431 Prospective Biological Sample Collection Aiming to Validate Non-invasive Prenatal Tests by Analyzing Fetal DNA Present in Maternal Blood Using a Next-generation Digital PCR Technique En recrutement 14 février 2025
NCT05901649 Prospective, Multi-Country, Observational Study of Clinical Outcomes for Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With ADT Plus Apalutamide or Enzalutamide Under Routine Clinical Practice (ArtemisPRO) En recrutement 14 février 2025
NCT06472778 Smoldering Pathway Assessment Real-World Knowledge (SPARK) Study-Retrospective Observational, Non-interventional Chart Review Study in Smoldering Multiple Myeloma En recrutement 07 décembre 2024
NCT04658329 Cohorte ANRS CO5 "Cohorte Nationale VIH2" Statut inconnu 15 juin 2024
NCT02861742 Evaluation of the Impact of Emotional Skills of Young Women (≤ 45 Years), With Non-metastatic Breast Cancer, and Their Partner on Adjustment to Cancer Statut inconnu 09 juin 2024
NCT02878408 Immuno-Génétique, Inflammation, Retro-Virus, Environnement En recrutement 09 juin 2024
NCT00418743 A Phase II Randomised Trial of Second-line Treatment in Patients With Small Cell Lung Cancer (SCLC), Comparing Oral Combination Chemotherapy (CCNU, Cyclophosphamide, Etoposide) With Intravenous Association Chemotherapy. Statut inconnu 09 juin 2024
NCT03306251 ANRS CO11 : National Cohort of Children Born to HIV-positive Mothers Statut inconnu 09 juin 2024