NCT Etude Statut Mise à jour
NCT03900221 French Registry for Monitoring Pregnancies and Children of Women With Multiple Sclerosis Within The Observatoire Français de la Sclérose en Plaque (OFSEP) Cohort (RESPONSE) En recrutement 13 mars 2025
NCT06078384 Adjuvant Pembrolizumab and Chemotherapy or Surveillance in Early Triple Negative breAst Cancer With High Stromal Tumor-infiltrating Lymphocytes (TILs) Score (ETNA) En recrutement 15 février 2025
NCT06057597 Randomized Controlled Non-inferiority Trial Evaluating the Safety and Efficacy of the Omega Gastric Bypass With 150 cm Biliopancreatic Loop Length Compared to the Roux-en-Y Gastric Bypass (YOMEGA-2) En recrutement 14 février 2025
NCT06494293 How Many Patients Suffering Major Trauma Would be Eligible for a Pre-hospital Transfusion: A Multicentre Retrospective Study. (TRAP) En recrutement 14 février 2025
NCT04411043 Prospective and Retrospective Study Evaluating Epidemiological, Clinical, Molecular and Therapeutic Data of Prolymphocytic Leukemia T (T-PLL) En recrutement 14 février 2025
NCT03976063 Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation: a Double-blinded Randomized Controlled Trial (TOCOPROM) En recrutement 14 février 2025
NCT05350826 Targeted Therapies in Chronic Lymphocytic Leukemia and Medico-economic Evaluation of the Ambulatory Medical Assistance Nurse Program : a Prospective Multicenter Randomized Study (THEMIS) En recrutement 14 février 2025
NCT06679608 Prospective Longitudinal Multicentric Study to Evaluate Syde® Digital Endpoints in Healthy Adults (Syde-CAR) En recrutement 14 février 2025
NCT03663725 Phase III Randomised Trial Evaluating Treatment Intensification With Temozolomide in Adults With a Glioblastoma (StrateGlio) En recrutement 14 février 2025
NCT04638725 Identification of Genetic Determinants for Treatment Resistance/Sensitivity and/or Toxicity in Adjuvant Setting for HER2 Positive Breast Cancer (SIGHER) En recrutement 14 février 2025
NCT04763447 Impact of Omalizumab Withdrawal After a 3 Year Duration Treatment in Well Controlled Severe Allergic Asthma : a Multicentric Randomized Controlled Trial (SHORTEN) En recrutement 14 février 2025
NCT04657783 French National Cohort of People With Type 1 Diabètes: the SFDT1 Study (SFDT1) En recrutement 14 février 2025
NCT04654923 Epidemiological Survey on Perioperative Hypersensitivity Reactions in France by the GERAP Network (Groupe d'étude Des réactions Anaphylactiques périopératoires) (SERAP) En recrutement 14 février 2025
NCT04685850 Long-term Sequelae of Childhood Meningitis and Meningococcal Purpura Fulminans in Ile de France: a Multidisciplinary Approach (SEINE) En recrutement 14 février 2025
NCT06551350 Retrospective Assessment of Referral of a Major Trauma Patient in Val-d'Oise (SAMU-TRAUMAS) En recrutement 14 février 2025
NCT05625087 A ctDNA Screening Program in Patients With HR+, HER2- Metastatic Breast Cancer for Detection of High-risk Relapse Patients on Any CDK4/6 Inhibitor and a Randomised Phase II Study Comparing Alpelisib Combined With Fulvestrant to Ribociclib Combined With Fulvestrant, in Patients With Persistent Targetable PIK3CA Mutations (SAFIR 03) En recrutement 14 février 2025
NCT06031805 a French Observational Prospective Multicenter Study of Adult Patients Treated in the Real-life Setting With Olaparib for the Treatment of Metastatic Castration-resistant Prostate Cancer (PROWESs) En recrutement 14 février 2025
NCT04188145 A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Metastatic Colorectal Cancer (BEVAMAINT) En recrutement 14 février 2025
NCT04325425 Folfirinox Versus Platinum - Etoposide as First Line Chemotherapy for Metastatic Grade 3 Poorly Differentiated Neuroendocrine Carcinoma of Gastro Entero Pancreatic and Unknown Primary Associated With Molecular Profiling for Therapeutic Targets & Predictive Biomarkers Identification (FOLFIRINEC) En recrutement 14 février 2025
NCT05565222 Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit (PITAGORE) En recrutement 14 février 2025
NCT06224764 Assessment of the Impact of the Return Home of Premature Newborns With Intrauterine Growth Retardation Weighing Less Than 2 Kilos (Low Birth Weight) on Short- and Long-term Morbidity/Mortality (Petit-Poids) En recrutement 14 février 2025
NCT05961488 Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest (PERFECCT) En recrutement 14 février 2025
NCT03819101 A Phase III Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer (PEACE-4) En recrutement 14 février 2025
NCT06318117 Observational Study on the Use of Infant Formulas Based on Rice Protein Hydrolysate in Real Life Conditions En recrutement 14 février 2025
NCT05539391 Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on Postintubation Morbidity: A Cluster Randomized Controlled Trial (OSETIM) En recrutement 14 février 2025
NCT05299840 Impact of Using the Oncogramme® Device to Select the First Line of Treatment (Chemotherapies +/- Targeted Therapies) for Patients With Metastatic Colorectal Cancer on Progression-free Survival, Treatment Costs, Efficiency and Quality of Life Compared to Usual Patient Care. En recrutement 14 février 2025
NCT04664569 National Observatory of Bacterial Meningitis in Children and Newborns En recrutement 14 février 2025
NCT05618431 Prospective Biological Sample Collection Aiming to Validate Non-invasive Prenatal Tests by Analyzing Fetal DNA Present in Maternal Blood Using a Next-generation Digital PCR Technique (NIPT) En recrutement 14 février 2025
NCT03875755 Reduction of Insulin Therapy Under Myo-inositol for the Treatment of Gestational Diabetes Mellitus: a Randomized Multicenter and Prospective Trial. MYO-GDM Study (MYO-GDM) En recrutement 14 février 2025
NCT06425367 Impact of Performing a Rapid Antibiotic Susceptibility Test (MHR-SIR) on Antibiotic Therapy Adaptation in Adult Patients with Enterobacterales Bacteremia, Controlled, Randomized Cluster and Cross-over Study (MHR-Blood) En recrutement 14 février 2025
NCT01522183 An Observational, Non-Interventional, Multi-Center, Multi-National Study of Patients With Atypical Hemolytic-Uremic Syndrome (aHUS Registry) En recrutement 14 février 2025
NCT05297617 Single-arm Study to De-escalate Adjuvant Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low Risk of Metastasis (LESS) En recrutement 14 février 2025
NCT04451915 Late Versus Early Management of Gestational Diabetes Mellitus: a Non Inferiority Randomized Multicenter Trial (LEMA_GDM) En recrutement 14 février 2025
NCT04174807 Prospective Study of Antenatal Diagnostic Criteria for Digestive Complications of Gastroschisis (LaparoDAN) En recrutement 14 février 2025
NCT05867225 Onlay Synthetic Bioabsorbable Mesh Herniorrhaphy Versus Herniorrhaphy Only in the Primary Treatment of Large Hiatal Hernia: a Multicenter, Randomized, Parallel-group, Evaluator Blinded, Phase III Clinical Trial (HIATUS) En recrutement 14 février 2025
NCT06261957 A Randomized, Double-blind, Parallel Group, Multi-center Study to Evaluate the Long-term Safety of Salbutamol Rescue Medication When Administered Via Metered Dose Inhalers Containing the Propellant HFA-152a or Reference HFA-134a En recrutement 14 février 2025
NCT06185491 Assessment of HGI (Hemoglobin Glycation Index) Variability Over Time in Patients Living with Diabetes Using Continuous Glucose Monitoring (GAP OUEST) En recrutement 14 février 2025
NCT05168839 Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage: a Single-blind Phase III Multicenter Randomized Controlled Trial (Intergroup FRENCH-GRECCAR Trial) (FLUOCOL-1) En recrutement 14 février 2025
NCT05232916 A Randomized, Multicenter, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of HER2/neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/neu Positive Subjects with Residual Disease or High-Risk PCR After Both Neoadjuvant and Postoperative Adjuvant Trastuzumab-based Therapy (FLAMINGO-01) (FLAMINGO-01) En recrutement 14 février 2025
NCT05590702 French Observational Study of Patients with Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma in Real-World Settings (FOLLOW) En recrutement 14 février 2025
NCT05596786 Evaluation de l'efficacité et de la sécurité du Rituximab Chez Les Patients Avec Une Pneumopathie Interstitielle Diffuse Progressive Avec Composante Inflammatoire : Essai Clinique randomisé Multicentrique en Double Insu Contre Placebo (EvER-ILD2) En recrutement 14 février 2025
NCT06169527 French Prospective Observational Study of Patients Receiving Dupilumab for Atopic Dermatitis. (DUPILAB) En recrutement 14 février 2025
NCT04890028 Detection and Metabolic Characterization in DOPA PET/CT of no Treated Brain Metastases of Lung Cancer, Breast Cancer and Melanoma (DOPACER) En recrutement 14 février 2025
NCT03656081 Therapeutic Efficacy Comparison of a Six-month Treatment by Itraconazole and Nebulised Ambisome® Versus Treatment by Itraconazole Alone in Non- or Mildly- Immunocompromised Patients with Chronic Pulmonary Aspergillosis: a Prospective, Randomized, Single Blind Study, (single Aspergilloma Excluded) En recrutement 14 février 2025
NCT05696093 Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit. Multicentric Non-inferiority Randomised Controlled Trial (COTRIVAP) En recrutement 14 février 2025
NCT05902117 Place of Copeptin-troponin Assay in the Elimination Diagnosis of Non-ST+ ACS in the Management of Pre-hospital and In-hospital Non-traumatic Chest Pain in Adults (CopSCA) En recrutement 14 février 2025
NCT04778657 National Exhaustive Cohort of Hereditary Stomatocytoses and Other Channelopathies Affecting the Red Blood Cell (COHSTO) En recrutement 14 février 2025
NCT01520844 Multicentric Cohort of HIV Patient With Extrem Profil (CODEX) En recrutement 14 février 2025
NCT05387954 Transcatheter Patent Foramen Ovale (PFO) Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Between 60 and 80 Years Old : a Randomised Controlled Trial. (CLOSE-2) En recrutement 14 février 2025
NCT03236987 CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI) En recrutement 14 février 2025
NCT04775381 Study of Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation (CAVITHY) En recrutement 14 février 2025
NCT06152575 A PHASE 3, OPEN-LABEL STUDY OF ELRANATAMAB MONOTHERAPY VERSUS ELOTUZUMAB, POMALIDOMIDE, DEXAMETHASONE (EPd) OR POMALIDOMIDE, BORTEZOMIB, DEXAMETHASONE (PVd) OR CARFILZOMIB, DEXAMETHASONE (Kd) IN PARTICIPANTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA WHO RECEIVED PRIOR ANTI-CD38 DIRECTED THERAPY En recrutement 14 février 2025
NCT05488288 Bariatric Surgery With Mesh Repair of Ventral Hernia: a Randomized Controlled Trial (BeSURE) En recrutement 14 février 2025
NCT05139784 BeAT1D: Benign Autoimmunity and Type 1 Diabetes (BeAT1D) En recrutement 14 février 2025
NCT05006859 Wheelchair Positioning and Neuromuscular Diseases Database (Retrospective and Prospective) (BDD-POSIT-MNM) En recrutement 14 février 2025
NCT02889965 The French Multiple Sclerosis Registry (OFSEP) En recrutement 14 février 2025
NCT05901649 Prospective, Multi-Country, Observational Study of Clinical Outcomes for Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With ADT Plus Apalutamide or Enzalutamide Under Routine Clinical Practice (ArtemisPRO) (ArtemisPRO) En recrutement 14 février 2025
NCT06268873 A Phase III, Randomised, Double-Blind, Active-controlled Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on Chronic Kidney Disease (CKD) Progression in Participants With CKD and High Blood Pressure En recrutement 14 février 2025
NCT03116217 Multicentre Validation of a Fetal Urine Peptidome-based Classifier to Predict Post-natal Renal Function in Posterior Urethral Valves (Antenatal) En recrutement 14 février 2025
NCT06368804 Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With Pseudomonas Aeruginosa in Adults With Bronchiectasis: a Non-inferiority Randomized Controlled Trial. (ANTEIPA) En recrutement 14 février 2025
NCT03148964 Multicentric Cohort of HIV-1 (Human Immunodeficiency Virus 1) Primary Infection Cohort ANRS CO6 PRIMO (PRIMO) En recrutement 14 février 2025
NCT04951856 Acute Myocardial Infarction Upbound to PCI Immediately (STEMI) or in the Next Three Days (NSTEMI), and Randomized to Subcutaneous Evolocumab or Normal Strategies to Reach Guidelines LDL Objectives in the Real-world - the AMUNDSEN-real Study (AMUNDSEN) En recrutement 14 février 2025
NCT04777916 A Prospective Non-interventional Study Documenting the Management and Outcomes of Adult Patients With Acute Myeloid Leukemia (AML) (ALFAPPP) En recrutement 14 février 2025
NCT04961528 ACid Tranexamic or Terlipressin for Initial Emergency Treatment of Mild to seVere hEmoptysis: a Randomized Trial. (ACTIVE) En recrutement 14 février 2025
NCT06472778 Smoldering Pathway Assessment Real-World Knowledge (SPARK) Study-Retrospective Observational, Non-interventional Chart Review Study in Smoldering Multiple Myeloma En recrutement 07 décembre 2024
NCT06298487 Evaluation of the Multidimensional Impact of Therapeutic Education Workshops for COPD Patients, Cared for by the Maison de Prévention de la Santé et d'Accompagnement Thérapeutique, in the North-West Val d'Oise Area (MPSAT-ETP) En recrutement 04 décembre 2024
NCT04658329 Cohorte ANRS CO5 "Cohorte Nationale VIH2" (ANRS CO VIH2) Statut inconnu 15 juin 2024
NCT02861742 Evaluation of the Impact of Emotional Skills of Young Women (≤ 45 Years), With Non-metastatic Breast Cancer, and Their Partner on Adjustment to Cancer (KALICOU3) Statut inconnu 09 juin 2024
NCT02878408 Immuno-Génétique, Inflammation, Retro-Virus, Environnement (I-Give) En recrutement 09 juin 2024
NCT00418743 A Phase II Randomised Trial of Second-line Treatment in Patients With Small Cell Lung Cancer (SCLC), Comparing Oral Combination Chemotherapy (CCNU, Cyclophosphamide, Etoposide) With Intravenous Association Chemotherapy. Statut inconnu 09 juin 2024
NCT03306251 ANRS CO11 : National Cohort of Children Born to HIV-positive Mothers (EPF) En recrutement 09 juin 2024