| NCT03875755 | Reduction of Insulin Therapy Under Myo-inositol for the Treatment of Gestational Diabetes Mellitus: a Randomized Multicenter and Prospective Trial. MYO-GDM Study | En recrutement | 25 octobre 2025 | 
            
                | NCT03976063 | Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation: a Double-blinded Randomized Controlled Trial | En recrutement | 25 octobre 2025 | 
            
                | NCT04184635 | Assessment of ECMO in Acute Myocardial Infarction With Non-reversible Cardiogenic Shock to Halt Organ Failure and Reduce Mortality (ANCHOR) | En recrutement | 25 octobre 2025 | 
            
                | NCT02905734 | Nicotine Replacement Therapy in Nicotine-dependent Arrestees: a Monocentric Randomized Simple Blind Study | En recrutement | 25 octobre 2025 | 
            
                | NCT02450396 | Prospective Observational Study About Pregnancy and Medically Assisted Conception in Rare Diseases | En recrutement | 25 octobre 2025 | 
            
                | NCT06518694 | Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction | En recrutement | 25 octobre 2025 | 
            
                | NCT06461065 | Evaluation of Neurodevelopmental Trajectories in Children According to the Glycemic Profile Associated With Different Early Treatment Modalities in Children With Type 1 Diabetes (T1DM) | En recrutement | 25 octobre 2025 | 
            
                | NCT05764057 | DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction | En recrutement | 25 octobre 2025 | 
            
                | NCT06057597 | Randomized Controlled Non-inferiority Trial Evaluating the Safety and Efficacy of the Omega Gastric Bypass With 150 cm Biliopancreatic Loop Length Compared to the Roux-en-Y Gastric Bypass | En recrutement | 25 octobre 2025 | 
            
                | NCT05488288 | Bariatric Surgery With Mesh Repair of Ventral Hernia: a Randomized Controlled Trial | En recrutement | 25 octobre 2025 | 
            
                | NCT05387954 | Transcatheter Patent Foramen Ovale (PFO) Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Between 60 and 80 Years Old : a Randomised Controlled Trial. | En recrutement | 25 octobre 2025 | 
            
                | NCT05565222 | Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit | En recrutement | 25 octobre 2025 | 
            
                | NCT06860269 | A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia | En recrutement | 25 octobre 2025 | 
            
                | NCT04961528 | ACid Tranexamic or Terlipressin for Initial Emergency Treatment of Mild to seVere hEmoptysis: a Randomized Trial. | En recrutement | 25 octobre 2025 | 
            
                | NCT05216731 | Bypass Versus Endovascular Procedure in Long Lesions of the Superficial Femoral Artery in the Claudicant | En recrutement | 25 octobre 2025 | 
            
                | NCT05247554 | Randomized Controlled Trial Testing the Effect of Hydroxychloroquine Combined With Low-dose Corticosteroid Therapy in Pulmonary Sarcoidosis | En recrutement | 25 octobre 2025 | 
            
                | NCT04554108 | Acute Non-severe Osteomyelitis in Children - Outpatient Management Strategy With Oral Antibiotic Therapy Compared to a Standard Strategy With Conventional Hospitalization and Intravenous Antibiotic Therapy: a Randomized Open-label Non-inferiority Study With Bayesian and Medical-economic Analyses. | En recrutement | 25 octobre 2025 | 
            
                | NCT04763447 | Impact of Omalizumab Withdrawal After a 3 Year Duration Treatment in Well Controlled Severe Allergic Asthma : a Multicentric Randomized Controlled Trial | En recrutement | 25 octobre 2025 | 
            
                | NCT05565222 | Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit | En recrutement | 27 septembre 2025 | 
            
                | NCT06494293 | How Many Patients Suffering Major Trauma Would be Eligible for a Pre-hospital Transfusion: A Multicentre Retrospective Study. | En recrutement | 18 septembre 2025 | 
            
                | NCT04411043 | Prospective and Retrospective Study Evaluating Epidemiological, Clinical, Molecular and Therapeutic Data of Prolymphocytic Leukemia T | En recrutement | 18 septembre 2025 | 
            
                | NCT05350826 | Targeted Therapies in Chronic Lymphocytic Leukemia and Medico-economic Evaluation of the Ambulatory Medical Assistance Nurse Program : a Prospective Multicenter Randomized Study | En recrutement | 18 septembre 2025 | 
            
                | NCT03663725 | Phase III Randomised Trial Evaluating Treatment Intensification With Temozolomide in Adults With a Glioblastoma | En recrutement | 18 septembre 2025 | 
            
                | NCT04638725 | Identification of Genetic Determinants for Treatment Resistance/Sensitivity and/or Toxicity in Adjuvant Setting for HER2 Positive Breast Cancer | En recrutement | 18 septembre 2025 | 
            
                | NCT04657783 | French National Cohort of People With Type 1 Diabètes: the SFDT1 Study | En recrutement | 18 septembre 2025 | 
            
                | NCT04654923 | Epidemiological Survey on Perioperative Hypersensitivity Reactions in France by the GERAP Network (Groupe d'étude Des réactions Anaphylactiques périopératoires) | En recrutement | 18 septembre 2025 | 
            
                | NCT04781790 | French National Registry of Bone Marrow Failures: Prospective and Retrospective Database Associated to a Collection of Biological Samples: RIME Project | En recrutement | 18 septembre 2025 | 
            
                | NCT03900221 | French Registry for Monitoring Pregnancies and Children of Women With Multiple Sclerosis Within The Observatoire Français de la Sclérose en Plaque (OFSEP) Cohort | En recrutement | 18 septembre 2025 | 
            
                | NCT06031805 | a French Observational Prospective Multicenter Study of Adult Patients Treated in the Real-life Setting With Olaparib for the Treatment of Metastatic Castration-resistant Prostate Cancer | En recrutement | 18 septembre 2025 | 
            
                | NCT06293625 | Personalising and Refining Neo-adjuvant Chemotherapy in Locally Advanced but Resecable Colon Cancer in the Elderly of 70 Years Old or More Phase III Multicentric Open-label Randomized Controlled Trial | En recrutement | 18 septembre 2025 | 
            
                | NCT03825861 | Neoadjuvant FOLFIRINOX in the Treatment of Locally Advanced Gastric Cancer | En recrutement | 18 septembre 2025 | 
            
                | NCT04188145 | A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Metastatic Colorectal Cancer | En recrutement | 18 septembre 2025 | 
            
                | NCT04325425 | Folfirinox Versus Platinum - Etoposide as First Line Chemotherapy for Metastatic Grade 3 Poorly Differentiated Neuroendocrine Carcinoma of Gastro Entero Pancreatic and Unknown Primary Associated With Molecular Profiling for Therapeutic Targets & Predictive Biomarkers Identification | En recrutement | 18 septembre 2025 | 
            
                | NCT06224764 | Assessment of the Impact of the Return Home of Premature Newborns With Intrauterine Growth Retardation Weighing Less Than 2 Kilos (Low Birth Weight) on Short- and Long-term Morbidity/Mortality | En recrutement | 18 septembre 2025 | 
            
                | NCT05961488 | Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest | En recrutement | 18 septembre 2025 | 
            
                | NCT03819101 | A Phase III Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer | En recrutement | 18 septembre 2025 | 
            
                | NCT06318117 | Observational Study on the Use of Infant Formulas Based on Rice Protein Hydrolysate in Real Life Conditions | En recrutement | 18 septembre 2025 | 
            
                | NCT05539391 | Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on Postintubation Morbidity: A Cluster Randomized Controlled Trial | En recrutement | 18 septembre 2025 | 
            
                | NCT05299840 | Impact of Using the Oncogramme® Device to Select the First Line of Treatment (Chemotherapies +/- Targeted Therapies) for Patients With Metastatic Colorectal Cancer on Progression-free Survival, Treatment Costs, Efficiency and Quality of Life Compared to Usual Patient Care. | En recrutement | 18 septembre 2025 | 
            
                | NCT04664569 | National Observatory of Bacterial Meningitis in Children and Newborns | En recrutement | 18 septembre 2025 | 
            
                | NCT02850705 | The French Cohort and Biobank of Devic's Neuromyelitis Optica and Related Neurological Disorders (NMOSD) (NOMADMUS) | En recrutement | 18 septembre 2025 | 
            
                | NCT06425367 | Impact of Performing a Rapid Antibiotic Susceptibility Test (MHR-SIR) on Antibiotic Therapy Adaptation in Adult Patients with Enterobacterales Bacteremia, Controlled, Randomized Cluster and Cross-over Study | En recrutement | 18 septembre 2025 | 
            
                | NCT06504615 | A French, Prospective, Observational, Multicenter Study of Patients Treated With Nivolumab Plus Chemotherapy as First Line Treatment in Advanced or Metastatic Esophageal Squamous Cell Carcinoma, Esophageal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma or Gastric Adenocarcinoma [METAGIO] | En recrutement | 18 septembre 2025 | 
            
                | NCT01522183 | An Observational, Non-Interventional, Multi-Center, Multi-National Study of Patients With Atypical Hemolytic-Uremic Syndrome (aHUS Registry) | En recrutement | 18 septembre 2025 | 
            
                | NCT04174807 | Prospective Study of Antenatal Diagnostic Criteria for Digestive Complications of Gastroschisis | En recrutement | 18 septembre 2025 | 
            
                | NCT04326218 | Immunopathological Analysis in a French National Cohort of Membranous Nephropathy (IHMN) | En recrutement | 18 septembre 2025 | 
            
                | NCT05867225 | Onlay Synthetic Bioabsorbable Mesh Herniorrhaphy Versus Herniorrhaphy Only in the Primary Treatment of Large Hiatal Hernia: a Multicenter, Randomized, Parallel-group, Evaluator Blinded, Phase III Clinical Trial | En recrutement | 18 septembre 2025 | 
            
                | NCT06450314 | De-escalation of Medical Therapies in HER2-positive Metastatic Breast Cancer in Long-term Persistent Response and Minimal Residual Disease Undetectable in Circulating Tumor DNA | En recrutement | 18 septembre 2025 | 
            
                | NCT06185491 | Assessment of HGI (Hemoglobin Glycation Index) Variability Over Time in Patients Living with Diabetes Using Continuous Glucose Monitoring | En recrutement | 18 septembre 2025 | 
            
                | NCT05168839 | Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage: a Single-blind Phase III Multicenter Randomized Controlled Trial (Intergroup FRENCH-GRECCAR Trial) | En recrutement | 18 septembre 2025 | 
            
                | NCT05232916 | A Randomized, Multicenter, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects With Residual Disease or High-Risk PCR After Both Neoadjuvant and Postoperative Adjuvant Trastuzumab-based Therapy (FLAMINGO-01) | En recrutement | 18 septembre 2025 | 
            
                | NCT06111586 | A 52-week Randomized, Double-blind, Placebo-controlled, Multi-center Phase 2b Study With a 52-week Blinded Extension Assessing Safety and Efficacy of Frexalimab, a CD40L-antagonist Monoclonal Antibody, for Preservation of Pancreatic β-cell Function in Adults and Adolescents With Newly Diagnosed Type 1 Diabetes on Insulin Therapy | En recrutement | 18 septembre 2025 | 
            
                | NCT05596786 | Evaluation de l'efficacité et de la sécurité du Rituximab Chez Les Patients Avec Une Pneumopathie Interstitielle Diffuse Progressive Avec Composante Inflammatoire : Essai Clinique randomisé Multicentrique en Double Insu Contre Placebo | En recrutement | 18 septembre 2025 | 
            
                | NCT06078384 | Adjuvant Pembrolizumab and Chemotherapy or Surveillance in Early Triple Negative breAst Cancer With High Stromal Tumor-infiltrating Lymphocytes (TILs) Score | En recrutement | 18 septembre 2025 | 
            
                | NCT06450990 | Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product (BGY-1601-VT) as a First-line Monotherapy in Women With Acute Vaginal Infection: a Randomized, Double-blind, Placebo-controlled Study | En recrutement | 18 septembre 2025 | 
            
                | NCT06679608 | Prospective Longitudinal Multicentric Study to Evaluate Syde® Digital Endpoints in Healthy Adults | En recrutement | 18 septembre 2025 | 
            
                | NCT05297617 | Single-arm Study to De-escalate Adjuvant Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low Risk of Metastasis | En recrutement | 18 septembre 2025 | 
            
                | NCT04451915 | Late Versus Early Management of Gestational Diabetes Mellitus: a Non Inferiority Randomized Multicenter Trial | En recrutement | 18 septembre 2025 | 
            
                | NCT06104566 | A Global Multicenter, Open Label, Randomized Phase 3 Registrational Study of Lisaftoclax (APG-2575) in Previously Treated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (GLORA Study) | En recrutement | 18 septembre 2025 | 
            
                | NCT06012006 | Determination of the Minimal Clinically Significant Difference (MCID) of Multidimensional Dyspnea Profile (MDP) Scores in Chronic Obstructive Pulmonary Disease (COPD) Patients During Pulmonary Rehabilitation | En recrutement | 18 septembre 2025 | 
            
                | NCT04890028 | Detection and Metabolic Characterization in DOPA PET/CT of no Treated Brain Metastases of Lung Cancer, Breast Cancer and Melanoma | En recrutement | 18 septembre 2025 | 
            
                | NCT04870203 | Combination of Baricitinib and Anti-TNF vs. Baricitinib in Patients With Rheumatoid Arthritis: a Randomized Controlled Phase III Trial | En recrutement | 18 septembre 2025 | 
            
                | NCT03656081 | Therapeutic Efficacy Comparison of a Six-month Treatment by Itraconazole and Nebulised Ambisome® Versus Treatment by Itraconazole Alone in Non- or Mildly- Immunocompromised Patients with Chronic Pulmonary Aspergillosis: a Prospective, Randomized, Single Blind Study, (single Aspergilloma Excluded) | En recrutement | 18 septembre 2025 | 
            
                | NCT04778657 | National Exhaustive Cohort of Hereditary Stomatocytoses and Other Channelopathies Affecting the Red Blood Cell | En recrutement | 18 septembre 2025 | 
            
                | NCT06353854 | National French Cohort Evaluating Predictive Factors of Resistance to Immunotherapy in Patients With MSI Metastatic Colorectal Cancer | En recrutement | 18 septembre 2025 | 
            
                | NCT01520844 | Multicentric Cohort of HIV Patient With Extrem Profil | En recrutement | 18 septembre 2025 | 
            
                | NCT03236987 | CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections | En recrutement | 18 septembre 2025 | 
            
                | NCT06834360 | A Randomized, Double-blind, Placebo-controlled, Parallel-group, 52-week Phase 3 Trial to Investigate the Efficacy, Safety, and Tolerability of Itepekimab in Adult Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps | En recrutement | 18 septembre 2025 | 
            
                | NCT06152575 | A PHASE 3, OPEN-LABEL STUDY OF ELRANATAMAB MONOTHERAPY VERSUS ELOTUZUMAB, POMALIDOMIDE, DEXAMETHASONE (EPd) OR POMALIDOMIDE, BORTEZOMIB, DEXAMETHASONE (PVd) OR CARFILZOMIB, DEXAMETHASONE (Kd) IN PARTICIPANTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA WHO RECEIVED PRIOR ANTI-CD38 DIRECTED THERAPY | En recrutement | 18 septembre 2025 | 
            
                | NCT05139784 | BeAT1D: Benign Autoimmunity and Type 1 Diabetes | En recrutement | 18 septembre 2025 | 
            
                | NCT05006859 | Wheelchair Positioning and Neuromuscular Diseases Database (Retrospective and Prospective) | En recrutement | 18 septembre 2025 | 
            
                | NCT02889965 | The French Multiple Sclerosis Registry | En recrutement | 18 septembre 2025 | 
            
                | NCT05768711 | Phase II Study With Safety run-in of Azacitidine (AZA) Combined With Venetoclax (VEN) in Patients With Higher-risk Chronic Myelomonocytic Leukemia (CMML) | En recrutement | 18 septembre 2025 | 
            
                | NCT06268873 | A Phase III, Randomised, Double-Blind Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on Chronic Kidney Disease (CKD) Progression in Participants With CKD and High Blood Pressure | En recrutement | 18 septembre 2025 | 
            
                | NCT03116217 | Multicentre Validation of a Fetal Urine Peptidome-based Classifier to Predict Post-natal Renal Function in Posterior Urethral Valves | En recrutement | 18 septembre 2025 | 
            
                | NCT06368804 | Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With Pseudomonas Aeruginosa in Adults With Bronchiectasis: a Non-inferiority Randomized Controlled Trial. | En recrutement | 18 septembre 2025 | 
            
                | NCT03148964 | Multicentric Cohort of HIV-1 (Human Immunodeficiency Virus 1) Primary Infection Cohort ANRS CO6 PRIMO | En recrutement | 18 septembre 2025 | 
            
                | NCT06533436 | Clinical and Economic Comparison of 2 Methods of Intubation Tube Fixation in the Intensive Care Unit: Benefits of Intubation Tube Fixation with AnchorFastTM Versus Current Cord Fixation | En recrutement | 18 septembre 2025 | 
            
                | NCT06512610 | Validation of the Use of the "ELN 2022" Risk Stratification System in HLA MENAFC Patients Newly Diagnosed With Acute Myeloid Leukemia | En recrutement | 18 septembre 2025 | 
            
                | NCT04777916 | A Prospective Non-interventional Study Documenting the Management and Outcomes of Adult Patients With Acute Myeloid Leukemia (AML) | En recrutement | 18 septembre 2025 | 
            
                | NCT05199051 | AGORA-1 /ALFA 2100 Study : a Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults with FLT3-ITD Relapse/refractory (R/R) AML | En recrutement | 18 septembre 2025 | 
            
                | NCT05002556 | AFU Registry of the Therapeutic Management and Follow-up of Non-Muscle-Invasive Bladder Cancer | En recrutement | 18 septembre 2025 | 
            
                | NCT06551350 | Retrospective Assessment of Referral of a Major Trauma Patient in Val-d'Oise | En recrutement | 14 février 2025 | 
            
                | NCT05625087 | A ctDNA Screening Program in Patients With HR+, HER2- Metastatic Breast Cancer for Detection of High-risk Relapse Patients on Any CDK4/6 Inhibitor and a Randomised Phase II Study Comparing Alpelisib Combined With Fulvestrant to Ribociclib Combined With Fulvestrant, in Patients With Persistent Targetable PIK3CA Mutations | En recrutement | 14 février 2025 | 
            
                | NCT05618431 | Prospective Biological Sample Collection Aiming to Validate Non-invasive Prenatal Tests by Analyzing Fetal DNA Present in Maternal Blood Using a Next-generation Digital PCR Technique | En recrutement | 14 février 2025 | 
            
                | NCT05901649 | Prospective, Multi-Country, Observational Study of Clinical Outcomes for Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With ADT Plus Apalutamide or Enzalutamide Under Routine Clinical Practice (ArtemisPRO) | En recrutement | 14 février 2025 | 
            
                | NCT06472778 | Smoldering Pathway Assessment Real-World Knowledge (SPARK) Study-Retrospective Observational, Non-interventional Chart Review Study in Smoldering Multiple Myeloma | En recrutement | 07 décembre 2024 | 
            
                | NCT04658329 | Cohorte ANRS CO5 "Cohorte Nationale VIH2" | Statut inconnu | 15 juin 2024 | 
            
                | NCT02861742 | Evaluation of the Impact of Emotional Skills of Young Women (≤ 45 Years), With Non-metastatic Breast Cancer, and Their Partner on Adjustment to Cancer | Statut inconnu | 09 juin 2024 | 
            
                | NCT02878408 | Immuno-Génétique, Inflammation, Retro-Virus, Environnement | En recrutement | 09 juin 2024 | 
            
                | NCT00418743 | A Phase II Randomised Trial of Second-line Treatment in Patients With Small Cell Lung Cancer (SCLC), Comparing Oral Combination Chemotherapy (CCNU, Cyclophosphamide, Etoposide) With Intravenous Association Chemotherapy. | Statut inconnu | 09 juin 2024 | 
            
                | NCT03306251 | ANRS CO11 : National Cohort of Children Born to HIV-positive Mothers | Statut inconnu | 09 juin 2024 |