Informations générales

750813321 Membre du GIRCI IDF
8610Z
Fondation
75

Adresse

  26 R D'ULM 75005 PARIS   Accès au plan

Contact pour la recherche clinique

n/c
n/c

Chiffres clés

Nombre de lits 224
Nombre de places 98
Nombre de passages aux urgences/an 0
Nombre d'accouchements/an 0

La recherche

Informations générales

Unité de recherche clinique
Nombre d'equivalents temps plein personnels de recherches Promotion : 24 ETP (chef de projet, ARC, biostatisticien, data manager) Investigation : 29 ETP (Coordinateur RC, ARC et TEC)
DRCI référente de proximité Institut Curie
Nombre d'essais dont l'établissement est promoteur 49
Nombre d'essais à finalité commerciale dont l'établissement est coordonateur 24
Nombre d'essais à finalité commerciale dont l'établissement est associé

Thématiques de recherche

  • oncologie
  • oncologie pédiatrique

Plateaux techniques

Hopital de jour
CRB
Scanner
IRM
Echographie
PUI
PUI avec préparation de chimiothérapie
Hémodialyse
Equipement de rééducation fonctionnelle
Bloc chirurgical
Bloc obstétrique
TEP

Listes des essais cliniques en recrutement

Etude Statut Dernière mise à jour
NCT02912949 A Phase I/II Study of MCLA-128, a Full Length IgG1 Bispecific Antibody Targeting HER2 and HER3, in Patients With Solid Tumors (eNRGy) En recrutement 28 décembre 2024
NCT06064877 A Multicenter, Randomized, Double Blind, Placebo - Controlled, Phase 3 Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV -Negative Head and Neck Squamous Cell Carcinoma. (FIERCE-HN) (FIERCE-HN) En recrutement 19 décembre 2024
NCT04934865 Real Life Prospective Multicentric Study Evaluating the Clinical and Organisational Impact of Moovcare® Lung Connected Medical Device in Lung Cancer Patients : REAL-MOOV-LUNG (REAL-MOOV-LUNG) En recrutement 14 décembre 2024
NCT04934865 Real Life Prospective Multicentric Study Evaluating the Clinical and Organisational Impact of Moovcare® Lung Connected Medical Device in Lung Cancer Patients : REAL-MOOV-LUNG (REAL-MOOV-LUNG) En recrutement 14 décembre 2024
NCT05514054 EMBER-4: A Randomized, Open-Label, Phase 3 Study of Adjuvant Imlunestrant vs Standard Adjuvant Endocrine Therapy in Patients Who Have Previously Received 2 to 5 Years of Adjuvant Endocrine Therapy for ER+, HER2- Early Breast Cancer With an Increased Risk of Recurrence (EMBER-4) En recrutement 11 décembre 2024
NCT05514054 EMBER-4: A Randomized, Open-Label, Phase 3 Study of Adjuvant Imlunestrant vs Standard Adjuvant Endocrine Therapy in Patients Who Have Previously Received 2 to 5 Years of Adjuvant Endocrine Therapy for ER+, HER2- Early Breast Cancer With an Increased Risk of Recurrence (EMBER-4) En recrutement 10 décembre 2024
NCT03526835 Phase 1/2 Dose Escalation and Cohort Expansion Study Evaluating MCLA-158 (Petosemtamab) as Single Agent or in Combination in Advanced Solid Tumors En recrutement 07 décembre 2024
NCT04299646 A Randomized Phase II Study Assessing Stereotactic Radiotherapy in Therapeutic Strategy of Oligoprogressive Renal Cell Carcinoma Metastases (GETUG-StORM-01) En recrutement 07 décembre 2024
NCT04221035 High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) (HR-NBL2) En recrutement 07 décembre 2024
NCT05296746 Neoadjuvant and Adjuvant Ribociclib and Endocrine Therapy for Clinically High-risk Estrogen Receptor-positive (ER+) and HER2-negative (HER2-) Breast Cancer (RIBOLARIS) En recrutement 07 décembre 2024
NCT03967834 Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group (MIRAS) En recrutement 07 décembre 2024
NCT04892173 A Phase 3 Study of NBTXR3 Activated by Investigator's Choice of Radiotherapy Alone or Radiotherapy in Combination With Cetuximab for Platinum-based Chemotherapy-Ineligible Elderly Patients With LA-HNSCC En recrutement 07 décembre 2024
NCT05617963 A Phase II Study of Durvalumab (MEDI 4736) Maintenance in Frail Limited Disease Small Cell Lung Cancer Patients After Thoracic Chemoradiotherapy (CRT) (DURVALUNG) En recrutement 07 décembre 2024
NCT05582850 A Phase 1, Multicentre, Open-label, Dose-escalation and Expansion Study to Determine a Recommended Phase 2 Dose (RP2D) of DT-9081 in Participants With Advanced Solid Tumours (EPRAD) En recrutement 07 décembre 2024
NCT05232916 A Randomized, Multicenter, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of HER2/neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/neu Positive Subjects with Residual Disease or High-Risk PCR After Both Neoadjuvant and Postoperative Adjuvant Trastuzumab-based Therapy (FLAMINGO-01) (FLAMINGO-01) En recrutement 07 décembre 2024
NCT06072781 A Phase 3, Randomized, Open-Label Study of Combination Therapy With Avutometinib Plus Defactinib Versus Investigator's Choice of Treatment in Patients With Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) (RAMP 301) (RAMP 301) En recrutement 07 décembre 2024
NCT04428554 Consolidative Radiotherapy for Metastatic Urothelial Bladder Cancer Patients Without Progression and With no More Than Three Residual Metastatic Lesions Following First Line Systemic Therapy: a Prospective Randomized Comparative Phase II Trial (BLAD-RAD01) En recrutement 07 décembre 2024
NCT04477681 Securing Access to Innovative Molecules in Oncology and Hematology for Children, Adolescents and Young Adults in Therapeutic Failure or Relapse and Not Eligible for a Clinical Trial: a Project of the SFCE (SACHA) En recrutement 07 décembre 2024
NCT02029001 A Two-period, Multicenter, Randomized, Open-label, Phase II Study Evaluating the Clinical Benefit of a Maintenance Treatment Targeting Tumor Molecular Alterations in Patients With Progressive Locally-advanced or Metastatic Solid Tumors (MOST plus) En recrutement 07 décembre 2024
NCT03983369 Multicenter Double Blind Randomized Placebo-controlled Trial Assessing the Efficacy of Low-level Laser Therapy in the Prevention of Chemotherapy-induced Mucositis in Children and Young Adults (MUCILA) En recrutement 07 décembre 2024
NCT04109131 A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours - BrainStorm Program (BrainStorm) En recrutement 07 décembre 2024
NCT05476939 Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication (BIOMEDE 2) En recrutement 07 décembre 2024
NCT05625412 A Phase 1, Open-label, Multicenter Study of BMS-986360/CC-90001 Alone and in Combination With Chemotherapy or Nivolumab in Advanced Solid Tumors En recrutement 07 décembre 2024
NCT05999994 CAMPFIRE: Children's and Young Adult Master Protocol for Innovative Pediatric Research (CAMPFIRE) En recrutement 07 décembre 2024
NCT05566795 LOGGIC/FIREFLY-2: a Phase 3, Randomized, International Multicenter Trial of DAY101 Monotherapy Versus Standard of Care Chemotherapy in Patients with Pediatric Low-Grade Glioma Harboring an Activating RAF Alteration Requiring First-Line Systemic Therapy En recrutement 07 décembre 2024
NCT03475953 A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors (REGOMUNE) En recrutement 07 décembre 2024
NCT05439005 Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study. (OFOBA) En recrutement 05 décembre 2024
NCT05434234 A Phase 1, Multicenter, Nonrandomized, Open-Label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of YL201 in Patients With Advanced Solid Tumors En recrutement 05 décembre 2024
NCT04183166 A Randomized Phase I/II Trial in Patients With Newly Diagnosed, Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN) Evaluating a Mutanome-directed Immunotherapy. En recrutement 05 décembre 2024
NCT04055220 A Randomized, Placebo-controlled, Double-blinded, Multicentre Study Evaluating the Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas (REGOSTA) En recrutement 05 décembre 2024
NCT03017573 Prospective Biobanking Study in Ovarian, Breast, Head and Neck and Cervical Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE) (SCANDARE) En recrutement 05 décembre 2024
NCT04823377 Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer. (PACT-01) En recrutement 05 décembre 2024
NCT04731610 Randomized, Multicenter, Phase III Trial to Assess Conformal Post-operative Radiotherapy vs. Surveillance After Complete Resection of Stage II/III Thymoma (RADIO-RYTHMIC) En recrutement 05 décembre 2024
NCT04790682 LIquid Biopsy to prEdict Responses To First-line immunotherapY in Metastatic Non-small Cell LUNG Cancer (LIBERTYLUNG) En recrutement 05 décembre 2024
NCT05180825 A Randomized and Controlled Phase II Protocol in Non NF1 Pediatric and AYA (Adolescent and Young Adults) Patients Bearing a Newly Diagnosed Low Grade Glioma With Wild Type BRAF Gene Comparing a Daily Oral MEK Inhibitor (Trametinib) Versus Weekly Vinblastine for 18 Months (PLGG - MEKTRIC) En recrutement 05 décembre 2024
NCT05354765 Exploration of Adaptive Antitumoral Immune Cells Through Lymphapheresis in Cancer Patients : ALCYTA (ALCYTA) En recrutement 05 décembre 2024
NCT05201547 Randomized Phase III Trial in MMR Deficient Endometrial Cancer Patients Comparing Chemotherapy Alone Versus Dostarlimab in First Line Advanced/Metastatic Setting (DOMENICA) En recrutement 05 décembre 2024
NCT04115007 Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients - a GETUG-AFU Phase III Randomized Controlled Trial (Oligo-PRESTO) En recrutement 05 décembre 2024
NCT05935098 A Phase 1a/1b Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-A3055, Alone and in Combination With Tislelizumab in Patients With Selected Advanced or Metastatic Solid Tumors En recrutement 05 décembre 2024
NCT05088395 Analysis of Circulating Tumor mArkers in Blood 4 - ALCINA 4 (ALCINA4) En recrutement 05 décembre 2024
NCT04698785 A Multicentre Phase II Study of Efficacy of Regorafenib as Maintenance Treatment in Patients With High Grade Bone Sarcomas at Diagnosis or Relapse and Without Complete Remission After Standard Treatment (REGOMAIN) En recrutement 05 décembre 2024
NCT04681417 Ocular Conservative Treatment for Retinoblastoma: Efficacy of the New Management Strategies and Visual Outcome - RETINO 2018 (RETINO2018) En recrutement 05 décembre 2024
NCT05424822 A Phase 1, First-in-human Study of JNJ-80948543, a T-cell Redirecting Antibody, in Participants With NHL and CLL En recrutement 05 décembre 2024
NCT04733027 Dose Escalation, First-in-human Clinical Trial to Evaluate the Safety, Pharmacokinetics and Preliminary Antitumor Activity of PEP-010, Administered As Single Agent and in Combination with Paclitaxel or with Gemcitabine in Patients with Metastatic Solid Cancer En recrutement 05 décembre 2024
NCT03838042 INFORM2 Exploratory Multinational Phase I/II Combination Study of Nivolumab and Entinostat in Children and Adolescents With Refractory High-risk Malignancies (INFORM2-NivEnt) En recrutement 05 décembre 2024
NCT04720729 Chemotherapy Monitoring by Circulating Tumor DNA (ctDNA) in HER2 (Human Epidermal Growth Factor Receptor-2)- Metastatic Breast Cancer (MONDRIAN): a Phase 2 Study (MONDRIAN) En recrutement 05 décembre 2024
NCT04143711 A Phase I/II, First-In-Human, Multi-Part, Open-Label, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological, and Clinical Activity of DF1001 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion in Selected Indications En recrutement 05 décembre 2024
NCT05293197 Phase I Trial Assessing the Safety of the Repeated Ultrasound-induced Opening of the Blood-brain Barrier in Pediatric Patients With Refractory Supra-tentorial Malignant Brain Tumors Before Chemotherapy Administration (SONOKID) En recrutement 05 décembre 2024
NCT04534205 An Open Label Phase II Randomized Trial of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Monotherapy as a First Line Therapy in Patients With Unresectable Recurrent, or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Which is Positive for Human Papilloma Virus 16 (HPV16+) and Expresses PD-L1 (AHEAD-MERIT) (AHEAD-MERIT) En recrutement 05 décembre 2024
NCT05634395 Digital Phenotyping (Physical Activity, Sleep) in Women Over 70 Years of Age Treated for Breast Cancer With Any Type of Treatment (GrannyFit) En recrutement 05 décembre 2024
NCT05781295 Multicentre Randomised Study Comparing a Taurolidine Lock and a Standard Saline Lock in the Primary Prevention of Catheter-related Endoluminal Infection in Paediatric Oncology. (PEDIALOCK) En recrutement 05 décembre 2024
NCT05987332 IDE196 (Darovasertib) in Combination With Crizotinib Versus Investigator's Choice of Treatment as First-line Therapy in HLA-A2 Negative Metastatic Uveal Melanoma (DAR-UM-2) En recrutement 05 décembre 2024
NCT06067061 "neoBREASTIM": A Phase 2 Study of Atezolizumab Plus RP1 Oncolytic Immunotherapy in the NeoAdjuvant Setting of Triple-Negative Breast Cancer (TNBC) (neoBREASTIM) En recrutement 05 décembre 2024
NCT06195709 ECLECTIC: EstroTEP and Circulating Biomarkers to Determine the Optimal Second Line Therapy for ER-positive HER2-negative Metastatic Breast Cancer Patients (ECLECTIC) En recrutement 05 décembre 2024
NCT05920356 A Phase 3, Multicenter, Randomized, Open-label Study Evaluating Efficacy of Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Subjects With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers, Negative for PD-L1, and Positive for KRAS p.G12C (CodeBreaK 202) En recrutement 05 décembre 2024
NCT05955170 Tucatinib in Combination With Oral Etoposide (VP16) - Trastuzumab in Patients With Metastatic HER2+ Breast Cancer After Progression Under Tucatinib-Capecitabine-Trastuzumab or Toxicity Related to Capecitabine: a Multicenter Phase II (TUC-TOC) En recrutement 05 décembre 2024
NCT05100862 A Phase 3 Randomized, Open-Label Multicenter Study of Zanubrutinib (BGB-3111) Plus Anti-CD20 Antibodies Versus Lenalidomide Plus Rituximab in Patients With Relapsed/Refractory Follicular or Marginal Zone Lymphoma (MAHOGANY) En recrutement 05 décembre 2024
NCT05730036 An Open-label, Randomized, Phase 3 Study of Linvoseltamab (REGN5458; Anti- BCMA x Anti-CD3 Bispecific Antibody) Versus the Combination of Elotuzumab, Pomalidomide, and Dexamethasone (EPd), in Patients With Relapsed/Refractory Multiple Myeloma (LINKER-MM3) (LINKER-MM3) En recrutement 05 décembre 2024
NCT06088290 Randomized, Controlled, Open-label, Phase IIb/III Study of Lurbinectedin in Combination with Doxorubicin Versus Doxorubicin Alone As First-line Treatment in Patients with Metastatic Leiomyosarcoma (SaLuDo) En recrutement 05 décembre 2024
NCT05445778 Randomized, Multicenter, Open-label, Phase 3 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients With FRα-high Recurrent Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Who Have Not Progressed After Second Line Platinum-based Chemotherapy Plus Bevacizumab (GLORIOSA) En recrutement 05 décembre 2024
NCT04529122 A Registry to Collect Characteristics and Outcomes From Patients With Solid Tumors Profiled With a Next-Generation Sequencing Test (WAYFIND-R) En recrutement 05 décembre 2024
NCT04424719 Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME) (SALOME) En recrutement 05 décembre 2024
NCT02870907 Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated En recrutement 05 décembre 2024
NCT05578976 A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With R-CHOP Compared to R-CHOP in Subjects With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) (EPCORE DLBCL-2) En recrutement 05 décembre 2024
NCT02884375 Elderly Cancer Patient: ELCAPA Cohort Survey (ELCAPA) En recrutement 04 décembre 2024
NCT04899505 ODORAJA:Evaluation of the Impact of Chemotherapy on Body Odor in Adolescents and Young Adults in Oncology (ODORAJA) En recrutement 04 décembre 2024
NCT05697146 Ribociclib Real-world Treatment Patterns and Clinical Outcomes Among Women With HR+/HER2- Advanced or Metastatic Breast Cancer in France: a National, Multicenter, Prospective, Non-interventional Study (RosaLEE) En recrutement 04 décembre 2024
NCT05630105 National Cohort of Patients With Cowden's Disease and With a Constitutional Alteration of the PTEN Gene for the Prospective Assessment of the Risk of Cancer. (COCO) En recrutement 04 décembre 2024
NCT01689584 Study of Family COsegregation of Nucleotide VARiants in the Panel of Genes to Validate Their Use in Genetic Counseling (COVAR) En recrutement 04 décembre 2024
NCT02265770 An International Clinical Program for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Ependymoma (SIOP-EP-II) En recrutement 04 décembre 2024
NCT02813135 European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors (ESMART) En recrutement 04 décembre 2024
NCT03246841 Investigation of Tumour Spectrum, Penetrance and Clinical Utility of Germline Mutations in New Breast and Ovarian Cancer Susceptibility Genes. (TUMOSPEC) En recrutement 04 décembre 2024
NCT03624244 Randomized Comparative Prospective Multicentre Phase II Trial Evaluating Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic LGESS (BFR-ESS) En recrutement 04 décembre 2024
NCT03340506 Open Label, Multi-center Roll-over Study to Assess Long Term Safety in Patients Who Have Completed a Global Novartis or GSK Sponsored Dabrafenib and/or Trametinib Study En recrutement 04 décembre 2024
NCT04236414 A Phase I, Open-label, Parallel Group Study to Investigate Olaparib Safety and Tolerability, Efficacy and Pharmacokinetics in Paediatric Patients With Solid Tumours En recrutement 04 décembre 2024
NCT04005820 Treatment for French Pediatric Patients With Renal Tumours According to the International SIOP Renal Tumour Study Group (RTSG) 2016 UMBRELLA Protocol Including Analysis of Tumour Chromosome 1q Gain and Central Radiology Review (UMBRELLA) En recrutement 04 décembre 2024
NCT03576417 A Phase III Randomized Trial of Post-operative Adjuvant Nivolumab and Concomitant Chemo-radiotherapy in High-risk Patients With Resected Squamous Cell Carcinoma of Head and Neck (NIVOPOSTOP) En recrutement 04 décembre 2024
NCT03622333 Clinic, Pathologic and Genetic Characterization of Patients With Familial Carcinoid Tumors (Study From the GTE, Groupe d'étude Des Tumeurs Endocrines) En recrutement 04 décembre 2024
NCT03830788 Erectile Dysfunction in Good Prognosis Prostate Cancer: a Phase III Medico-economic Study Comparing Brachytherapy to Stereotactic Body Radiotherapy (TEMPOS) En recrutement 04 décembre 2024
NCT04241185 A Phase 3, Randomized, Double-blind, Placebo-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Participants With Muscle-invasive Bladder Cancer (MIBC) (KEYNOTE-992) En recrutement 04 décembre 2024
NCT04544995 A PHASE 1, MULTICENTRE, OPEN-LABEL, DOSE-ESCALATION AND COHORT EXPANSION STUDY OF NIRAPARIB AND DOSTARLIMAB IN PAEDIATRIC PATIENTS WITH RECURRENT OR REFRACTORY SOLID TUMOURS En recrutement 04 décembre 2024
NCT04774718 A Phase I/II, Open-Label, Multicenter, Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors for Whom Prior Treatment Has Proven to be Ineffective or for Whom There is No Satisfactory Treatment Available En recrutement 04 décembre 2024
NCT02897986 (PROVIN) En recrutement 04 décembre 2024
NCT04526782 A Phase II Study of the BRAF Inhibitor Encorafenib in Combination with the MEK Inhibitor Binimetinib in Patients with BRAFV600E-mutant Metastatic Non-small Cell Lung Cancer (ENCO-BRAF) En recrutement 04 décembre 2024
NCT04025541 Analysis of Circulating Tumor Markers in Blood (ALCINA 2) En recrutement 04 décembre 2024
NCT05403554 A Phase 1, Open-Label, Dose Finding Study of NI-1801, a Bispecific Mesothelin X CD47 Engaging Antibody, As a Single Agent, in Combination with Anti-PD-1 Antibody, and in Combination with Weekly Paclitaxel (Standard of Care) in Patients with Mesothelin Expressing Ovarian, Pancreatic, Non-Small-Cell-Lung and Triple-Negative Breast Cancers En recrutement 04 décembre 2024
NCT04243499 A First-in-human, Two-part Clinical Study to Assess the Safety, Tolerability and Activity of IV Doses of ICT01 as Monotherapy and in Combination With a Checkpoint Inhibitor, in Patients With Advanced-stage, Relapsed/Refractory Cancer (EVICTION) En recrutement 04 décembre 2024
NCT03772028 Phase III Randomized Clinical Trial for Stage III Epithelial Ovarian Cancer Randomizing Between Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (OVHIPEC-2) En recrutement 04 décembre 2024
NCT05296798 A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Giredestrant in Combination With Phesgo Versus Phesgo After Induction Therapy With Phesgo + Taxane in Patients With Previously Untreated HER2-Positive, Estrogen Receptor-Positive Locally-Advanced or Metastatic Breast Cancer En recrutement 04 décembre 2024
NCT05415072 A Phase I/II, Multi-center, Open Label Study of DYP688 in Patients With Metastatic Uveal Melanoma (MUM) and Other GNAQ/11 Mutant Melanomas En recrutement 04 décembre 2024
NCT05208762 A Phase 1 Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors En recrutement 04 décembre 2024
NCT05441163 ProActIF-01 Trial: Randomized Study of Evaluation of an Individualized Program of Nutrition and Adapted Physical Activity in Frail Patients With Advanced Lung or Digestive Cancers (ProActIF-01) En recrutement 04 décembre 2024
NCT05099172 An Open Label, First-in-human Study of BAY 2927088 in Participants With Advanced Non-small Cell Lung Cancer (NSCLC) Harboring an EGFR and/or HER2 Mutation En recrutement 04 décembre 2024
NCT05498428 A Phase 2, Open-Label, Parallel Cohort Study of Subcutaneous Amivantamab in Multiple Regimens in Patients With Advanced or Metastatic Solid Tumors Including EGFR-mutated Non-Small Cell Lung Cancer (PALOMA-2) En recrutement 04 décembre 2024
NCT04625907 FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma (FaR-RMS) En recrutement 04 décembre 2024
NCT05925530 A Multicentre, Phase II, Single-Arm, Interventional Study of Neoadjuvant Durvalumab and Platinum-based Chemotherapy (CT), Followed by Either Surgery and Adjuvant Durvalumab or Chemoradiotherapy (CRT) and Consolidation Durvalumab, in Participants With Resectable or Borderline Resectable Stage IIB-IIIB Non-small Cell Lung Cancer (NSCLC) (MDT-BRIDGE) En recrutement 04 décembre 2024
NCT05830084 Phase Ib Study of the Combination of Regorafenib With Conventional Chemotherapy for the Treatment of Newly Diagnosed Patients With Multimetastatic Ewing Sarcoma (REGO-INTER-EWI) En recrutement 04 décembre 2024
NCT05116475 Evaluation of dAroLutamide Addition to anDrogen Deprivation Therapy and radIatioN Therapy in Newly Diagnosed Prostate Cancer With Pelvic Lymph Nodes Metastases (ALADDIN) En recrutement 04 décembre 2024
NCT05192980 SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours (BIOPORTAL) En recrutement 04 décembre 2024
NCT05691608 MoleculAr Profiling for Pediatric and Young Adult Cancer Treatment Stratification 2 (MAPPYACTS2) En recrutement 04 décembre 2024
NCT05210413 Spartalizumab and Low-dose PAzopanib in Refractory or Relapsed Solid TumOrs of Pediatric and Adults (SPARTO) En recrutement 04 décembre 2024
NCT05261399 A Phase III, Randomised, Open-Label Study of Savolitinib in Combination With Osimertinib Versus Platinum-Based Doublet Chemotherapy in Participants With EGFR Mutated, MET-Overexpressed and/or Amplified, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Progressed on Treatment With Osimertinib (SAFFRON). (SAFFRON) En recrutement 04 décembre 2024
NCT06007092 Multicentric Randomized Phase I/IIa Trial of the Safety and Immunogenicity of a Therapeutic Anti-HPV DC Targeting Vaccine in Patients With Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer (HPVDCVax) En recrutement 04 décembre 2024
NCT06062420 A Phase 2, Randomized, Open-label, Platform Study Using a Master Protocol to Evaluate Novel Immunotherapy Combinations as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck En recrutement 04 décembre 2024
NCT06162351 A Phase II Study to Evaluate the Efficacy and Toxicities of PLX038, in Patients With Locally Advanced or Metastatic Triple-negative Breast Cancer (TOPOLOGY) En recrutement 04 décembre 2024
NCT06175390 Tiragolumab, Atezolizumab and Chemotherapy in Triple Negative Breast Cancer: A Phase II Trial (SKYLINE) En recrutement 04 décembre 2024
NCT05529862 Trans-RosaLEE Study: a Biomarker-directed, Translational Study of High-throughput Molecular Profiling of HR+/HER2- Metastatic Breast Cancer Treated With Endocrine Therapy and Ribociclib. (TransRosaLEE) En recrutement 04 décembre 2024
NCT04262466 Phase 1/2 Study of IMC-F106C in Advance PRAME-Positive Cancers En recrutement 04 décembre 2024
NCT05967689 An Open-Label, Phase 2b, Global Multicenter Cohort Trial to Assess the Safety and Efficacy of Zipalertinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Exon 20 Insertion and Uncommon/Single or Compound Epidermal Growth Factor Receptor Mutations. (REZILIENT2) En recrutement 04 décembre 2024
NCT05794906 A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Darolutamide Plus Androgen Deprivation Therapy (ADT) Compared With Placebo Plus ADT in Patients With High-risk Biochemical Recurrence (BCR) of Prostate Cancer (ARASTEP) En recrutement 04 décembre 2024
NCT05990738 DAREON™-9: A Phase Ib Open-label Dose Escalation and Dose Confirmation Safety Study of Intravenous BI 764532 in Combination With a Single Agent Chemotherapy for the Treatment of Patients With Relapsed/Refractory Small Cell Lung Cancer After Platinum-based Chemotherapy En recrutement 04 décembre 2024
NCT05907954 (Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma En recrutement 04 décembre 2024
NCT05652868 A Phase 1 Multicenter Dose Escalation and Dose Expansion Study of Antibody-Drug Conjugate MYTX-011 in Subjects With Non-Small Cell Lung Cancer - KisMET-01 En recrutement 04 décembre 2024
NCT05973773 Randomized, Controlled, Open-label, Phase 3, Global Multi - Center Trial to Assess the Efficacy and Safety of Zipalertinib Plus Chemotherapy Versus Chemotherapy Alone, in Patients With Previously Untreated, Locally Advanced or Metastatic Nonsquamous Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations (REZILIENT3) En recrutement 04 décembre 2024
NCT06151574 Beamion LUNG 2: A Phase III, Open-label, Randomized, Active-controlled, Multi-centre Trial Evaluating Orally Administered Zongertinib (BI 1810631) Compared With Standard of Care as First-line Treatment in Patients With Unresectable, Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer Harbouring HER2 Tyrosine Kinase Domain Mutations En recrutement 04 décembre 2024
NCT05984277 A Phase III, Two-Arm, Parallel, Randomized, Multi-Center, Open-Label, Global Study to Determine the Efficacy of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for First-Line Treatment of Patients With Metastatic Non-Small Cell Lung Cancer (mNSCLC). (eVOLVE-Lung02) En recrutement 04 décembre 2024
NCT05939414 An International, Prospective, Open-label, Multi-center, Randomized Phase III Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) Versus Observation to Delay Castration or Disease Recurrence in Adult Male Patients With Prostate-specific Membrane Antigen (PSMA) Positive Oligometastatic Prostate Cancer (OMPC) (PSMA-DC) En recrutement 04 décembre 2024
NCT06162221 A Platform Study of RAS(ON) Inhibitor Combinations in Patients with RAS-Mutated Non-Small Cell Lung Cancer (NSCLC) En recrutement 04 décembre 2024
NCT06349512 68Ga-FAPI-46 PET/CT for Predicting Histological Response to Neoadjuvant Chemo-immunotherapy in Triple-negative Breast Cancer (FAP-IT) En recrutement 04 décembre 2024
NCT05512364 Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) En recrutement 04 décembre 2024
NCT06312176 An Open-label, Randomized Phase 3 Study of MK-2870 as a Single Agent and in Combination With Pembrolizumab Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer En recrutement 04 décembre 2024
NCT06108479 A Phase 1/1b, First-In-Human, Multi-Part, Open-Label Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of DF6215 in Patients With Advanced (Unresectable, Recurrent, or Metastatic) Solid Tumors En recrutement 04 décembre 2024
NCT06452277 A Phase 3 Open-label, Randomized, Active-controlled, Multicenter Trial to Evaluate the Efficacy and Safety of Orally Administered BAY 2927088 Compared With Standard of Care as a First-line Therapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With HER2-activating Mutations (SOHO-02) En recrutement 04 décembre 2024
NCT06246149 Adjuvant Tebentafusp (IMCgp100) Versus Observation in HLA-A*02:01 Positive Patients Following Definitive Treatment of High-risk Uveal Melanoma: an EORTC Randomized Phase III Study (ATOM Trial) (ATOM) En recrutement 04 décembre 2024
NCT06074588 A Randomized, Open-label, Phase 3 Study of MK-2870 vs Chemotherapy (Docetaxel or Pemetrexed) in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations En recrutement 04 décembre 2024
NCT02884375 Elderly Cancer Patient: ELCAPA Cohort Survey (ELCAPA) En recrutement 04 décembre 2024
NCT05697146 Ribociclib Real-world Treatment Patterns and Clinical Outcomes Among Women With HR+/HER2- Advanced or Metastatic Breast Cancer in France: a National, Multicenter, Prospective, Non-interventional Study (RosaLEE) En recrutement 04 décembre 2024
NCT05630105 National Cohort of Patients With Cowden's Disease and With a Constitutional Alteration of the PTEN Gene for the Prospective Assessment of the Risk of Cancer. (COCO) En recrutement 04 décembre 2024
NCT05440331 Morbidity and Mortality in Operating Room: Surgery and Standardized Communication (HIATUS) En recrutement 04 décembre 2024
NCT01689584 Study of Family COsegregation of Nucleotide VARiants in the Panel of Genes to Validate Their Use in Genetic Counseling (COVAR) En recrutement 04 décembre 2024
NCT02416388 Phase II/III Randomized Study to Improve Overall Survival in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus Mycophenolate Mofetil Prophylaxis of Graft Versus Host Disease in Allografted Patients in First CR : a Backbone InterGroup-1 Trial (BIG-1) En recrutement 04 décembre 2024
NCT03017573 Prospective Biobanking Study in Ovarian, Breast, Head and Neck and Cervical Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE) (SCANDARE) En recrutement 04 décembre 2024
NCT02355379 Randomised Phase III Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over Intergroup Trial: Ffcd, Gercor, Gerico, Unicancer-gi (ADAGE) En recrutement 04 décembre 2024
NCT03246841 Investigation of Tumour Spectrum, Penetrance and Clinical Utility of Germline Mutations in New Breast and Ovarian Cancer Susceptibility Genes. (TUMOSPEC) En recrutement 04 décembre 2024
NCT03774732 PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer (NIRVANA-LUNG) En recrutement 04 décembre 2024
NCT03576417 A Phase III Randomized Trial of Post-operative Adjuvant Nivolumab and Concomitant Chemo-radiotherapy in High-risk Patients With Resected Squamous Cell Carcinoma of Head and Neck (NIVOPOSTOP) En recrutement 04 décembre 2024
NCT02912949 A Phase I/II Study of MCLA-128, a Full Length IgG1 Bispecific Antibody Targeting HER2 and HER3, in Patients With Solid Tumors (eNRGy) En recrutement 04 décembre 2024
NCT03830788 Erectile Dysfunction in Good Prognosis Prostate Cancer: a Phase III Medico-economic Study Comparing Brachytherapy to Stereotactic Body Radiotherapy (TEMPOS) En recrutement 04 décembre 2024
NCT03876951 Prospective Multicenter Pilot Study to Evaluate the Accuracy of Percutaneous Biopsy by Vacuum-assisted Biopsy (VAB) to Assess Pathological Complete Response in Patients With Clinical and Radiological Complete Response After Neoadjuvant Chemotherapy (NeoVAB) (NeoVAB) En recrutement 04 décembre 2024
NCT04290663 Multicentric Phase III Trial Comparing Two Strategies in Intermediate-risk Differentiated Thyroid Cancer Patients: Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up Based on Serum Tg Values and Diagnostic RAI Scintigraphy (INTERMEDIATE) En recrutement 04 décembre 2024
NCT04720729 Chemotherapy Monitoring by Circulating Tumor DNA (ctDNA) in HER2 (Human Epidermal Growth Factor Receptor-2)- Metastatic Breast Cancer (MONDRIAN): a Phase 2 Study (MONDRIAN) En recrutement 04 décembre 2024
NCT04790682 LIquid Biopsy to prEdict Responses To First-line immunotherapY in Metastatic Non-small Cell LUNG Cancer (LIBERTYLUNG) En recrutement 04 décembre 2024
NCT04823377 Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer. (PACT-01) En recrutement 04 décembre 2024
NCT04025541 Analysis of Circulating Tumor Markers in Blood (ALCINA 2) En recrutement 04 décembre 2024
NCT05354765 Exploration of Adaptive Antitumoral Immune Cells Through Lymphapheresis in Cancer Patients : ALCYTA (ALCYTA) En recrutement 04 décembre 2024
NCT05088395 Analysis of Circulating Tumor mArkers in Blood 4 - ALCINA 4 (ALCINA4) En recrutement 04 décembre 2024
NCT05296746 Neoadjuvant and Adjuvant Ribociclib and Endocrine Therapy for Clinically High-risk Estrogen Receptor-positive (ER+) and HER2-negative (HER2-) Breast Cancer (RIBOLARIS) En recrutement 04 décembre 2024
NCT05475366 Pilot Study of Personalized First-line Chemotherapy Choice for Patients With Advanced Pancreatic Adenocarcinoma Using Transcriptomic Signatures (PACsign) (PACsign) En recrutement 04 décembre 2024
NCT05439005 Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study. (OFOBA) En recrutement 04 décembre 2024
NCT05634395 Digital Phenotyping (Physical Activity, Sleep) in Women Over 70 Years of Age Treated for Breast Cancer With Any Type of Treatment (GrannyFit) En recrutement 04 décembre 2024
NCT05441163 ProActIF-01 Trial: Randomized Study of Evaluation of an Individualized Program of Nutrition and Adapted Physical Activity in Frail Patients With Advanced Lung or Digestive Cancers (ProActIF-01) En recrutement 04 décembre 2024
NCT05116475 Evaluation of dAroLutamide Addition to anDrogen Deprivation Therapy and radIatioN Therapy in Newly Diagnosed Prostate Cancer With Pelvic Lymph Nodes Metastases (ALADDIN) En recrutement 04 décembre 2024
NCT05665530 A Phase 1 Open-Label, Multi-Center, Safety and Efficacy Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With Relapsed/Refractory Hematologic Malignancies En recrutement 04 décembre 2024
NCT05955170 Tucatinib in Combination With Oral Etoposide (VP16) - Trastuzumab in Patients With Metastatic HER2+ Breast Cancer After Progression Under Tucatinib-Capecitabine-Trastuzumab or Toxicity Related to Capecitabine: a Multicenter Phase II (TUC-TOC) En recrutement 04 décembre 2024
NCT06084936 A Phase III, Open-Label, Multicenter Randomized Study Evaluating Glofitamab as a Single Agent Versus Investigator's Choice in Patients With Relapsed/Refractory Mantle Cell Lymphoma (GLOBRYTE) En recrutement 04 décembre 2024
NCT06162351 A Phase II Study to Evaluate the Efficacy and Toxicities of PLX038, in Patients With Locally Advanced or Metastatic Triple-negative Breast Cancer (TOPOLOGY) En recrutement 04 décembre 2024
NCT06175390 Tiragolumab, Atezolizumab and Chemotherapy in Triple Negative Breast Cancer: A Phase II Trial (SKYLINE) En recrutement 04 décembre 2024
NCT03328078 An Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered CA-4948 in Patients with Relapsed or Refractory Primary Central Nervous System Lymphoma En recrutement 04 décembre 2024
NCT06275737 Trimodal Peri Operative Prehabilitation for Upper Oesogastric and Pancreatic Cancer: A Multicenter, Two-cohort, Open-label, Single-arm POP-UP GERCOR Study (POP-UP) En recrutement 04 décembre 2024
NCT06195709 ECLECTIC: EstroTEP and Circulating Biomarkers to Determine the Optimal Second Line Therapy for ER-positive HER2-negative Metastatic Breast Cancer Patients (ECLECTIC) En recrutement 04 décembre 2024
NCT05794906 A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Darolutamide Plus Androgen Deprivation Therapy (ADT) Compared With Placebo Plus ADT in Patients With High-risk Biochemical Recurrence (BCR) of Prostate Cancer (ARASTEP) En recrutement 04 décembre 2024
NCT05232916 A Randomized, Multicenter, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of HER2/neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/neu Positive Subjects with Residual Disease or High-Risk PCR After Both Neoadjuvant and Postoperative Adjuvant Trastuzumab-based Therapy (FLAMINGO-01) (FLAMINGO-01) En recrutement 04 décembre 2024
NCT06284122 A Phase III Randomized, Open-label, International, Multicenter Study Evaluating the Efficacy and Safety of Mosunetuzumab Plus Lenalidomide in Comparison to Anti-CD20 Monoclonal Antibody Plus Chemotherapy in Subjects With Previously Untreated FLIPI 2-5 Follicular Lymphoma (MorningLyte) En recrutement 04 décembre 2024
NCT05939414 An International, Prospective, Open-label, Multi-center, Randomized Phase III Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) Versus Observation to Delay Castration or Disease Recurrence in Adult Male Patients With Prostate-specific Membrane Antigen (PSMA) Positive Oligometastatic Prostate Cancer (OMPC) (PSMA-DC) En recrutement 04 décembre 2024
NCT06349512 68Ga-FAPI-46 PET/CT for Predicting Histological Response to Neoadjuvant Chemo-immunotherapy in Triple-negative Breast Cancer (FAP-IT) En recrutement 04 décembre 2024
NCT05512364 Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) En recrutement 04 décembre 2024
NCT05731661 Optimize the Support of Patients in Pelvic Onco-gynecology Through Adapted Support Care in the Post-cancer Period. AFTERGYN Pilot Phase (AFTERGYN) En recrutement 04 décembre 2024
NCT06356129 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Golcadomide Plus R-CHOP Chemotherapy vs Placebo Plus R-CHOP Chemotherapy in Participants With Previously Untreated High-risk Large B-cell Lymphoma (GOLSEEK-1) (GOLSEEK-1) En recrutement 04 décembre 2024
NCT06413706 A Randomized, Open-Label, Phase 2 Study Evaluating Abemaciclib in Combination With Temozolomide Compared to Temozolomide Monotherapy in Children and Young Adults With Newly Diagnosed High-Grade Glioma Following Radiotherapy En recrutement 23 novembre 2024
NCT06622486 First-in-human Phase 1/2 Trial of EGL-001 in Adult Patients with Selected Advanced And/or Metastatic Solid Tumors En recrutement 08 novembre 2024
NCT06660147 PAOLA-1 Ancillary Study: Retrospective Validation of KELIM as a Predictive and Prognostic Factor for Maintenance Treatment With PARP Inhibitor After Platinum-Based Chemotherapy in First-Line Ovarian Cancer (KELI-PAOLA) En recrutement 29 octobre 2024
NCT04652076 A Randomized, Multicenter, Open Label, Phase I/II Study to Evaluate the Safety, Clinical and Biological Activity of a Humanized Monoclonal Antibody Targeting Netrin-1 (NP137) in Combination with Carboplatin Plus Paclitaxel And/or Pembrolizumab in Patients with Locally Advanced/metastatic Endometrial Carcinoma or Cervix Carcinoma Progressing/relapsing After At Least One Prior Systemic Chemotherapy. (GYNET) En recrutement 09 octobre 2024
NCT06599463 Efficacy Assessment of Lenvatinib Associated with Pembrolizumab in Metastatic Endometrial Cancer: a French Multicentric Retrospective Early Access Program-based Study (LARENA) En recrutement 20 septembre 2024
NCT03774732 PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer (NIRVANA-LUNG) En recrutement 20 septembre 2024
NCT05963997 A Phase 1b/2 Open-label Study of Samuraciclib in Combination With Elacestrant in Participants With Metastatic or Locally Advanced Hormone Receptor-positive and Human Epidermal Growth Factor Receptor 2-negative Breast Cancer (SUMIT-ELA) En recrutement 05 septembre 2024
NCT03622333 Clinic, Pathologic and Genetic Characterization of Patients With Familial Carcinoid Tumors (Study From the GTE, Groupe d'étude Des Tumeurs Endocrines) En recrutement 07 août 2024
NCT05132582 A Randomized, Double-blind, Phase 3 Study of Tucatinib or Placebo in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy for Metastatic HER2+ Breast Cancer (HER2CLIMB-05) (HER2CLIMB-05) En recrutement 17 juillet 2024
NCT03328078 An Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered CA-4948 in Patients with Relapsed or Refractory Primary Central Nervous System Lymphoma En recrutement 16 juillet 2024
NCT03553420 Osse Registry for Patients With Lipodystrophy Run by the European Consortium of Lipodystrophies (ECLip) (ECLip Registry) En recrutement 15 juin 2024
NCT00875355 Phase II Randomized Multicenter Study Comparing Brain Radiation in Combination With Temozolomide or Radiation Alone in Patients With Brain Metastases From Breast Cancer Statut inconnu 15 juin 2024
NCT04994730 Exenteration: Quality of Life Study and Rehabilitation Rate According to the Reconstruction Technique (ETRE) Statut inconnu 15 juin 2024
NCT04928846 A Phase 3 Open-Label, Randomized, Controlled, Global Study of Telisotuzumab Vedotin (ABBV-399) Versus Docetaxel in Subjects With Previously Treated c-Met Overexpressing, EGFR Wildtype, Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer En recrutement 15 juin 2024
NCT03818386 Radiotherapy of Multiple Brain Metastases Using AGuIX® Gadolinium-chelated Polysiloxane Based Nanoparticles: a Prospective Randomized Phase II Clinical Trial. (NANORAD2) En recrutement 15 juin 2024
NCT04210115 A Randomized, Double-blind, Placebo-controlled Phase 3 Trial of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Receiving Concurrent Definitive Chemoradiotherapy (KEYNOTE 975) En recrutement 10 juin 2024
NCT02416388 Phase II/III Randomized Study to Improve Overall Survival in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus Mycophenolate Mofetil Prophylaxis of Graft Versus Host Disease in Allografted Patients in First CR : a Backbone InterGroup-1 Trial (BIG-1) En recrutement 04 juin 2024
NCT03876951 Prospective Multicenter Pilot Study to Evaluate the Accuracy of Percutaneous Biopsy by Vacuum-assisted Biopsy (VAB) to Assess Pathological Complete Response in Patients With Clinical and Radiological Complete Response After Neoadjuvant Chemotherapy (NeoVAB) (NeoVAB) En recrutement 04 juin 2024
NCT04290663 Multicentric Phase III Trial Comparing Two Strategies in Intermediate-risk Differentiated Thyroid Cancer Patients: Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up Based on Serum Tg Values and Diagnostic RAI Scintigraphy (INTERMEDIATE) En recrutement 04 juin 2024
NCT05685628 Evaluation of the Quality of Life Induced by the Cinnamon Anti-odor Dressing in Patients With Malodorous Wounds: a Multicenter Randomized Controlled Trial (CINNAMON) En recrutement 22 mars 2024
NCT02724696 French National Observatory of Patients With Thymic Epithelial Tumor (RYTHMIC) En recrutement 21 novembre 2023
NCT05558644 Characterisation of the Immune Infiltrate and Molecular Features of Thymic Epithelial Tumors Tumors (TETs) (IMMUNO-TET) En recrutement 21 novembre 2023
NCT01217398 Phase II Single-Center Study of Bevacizumab in Combination With Temozolomide in Patients With First-Line Metastatic Uveal Melanoma Statut inconnu 21 novembre 2023
NCT00897728 Colon and Breast Cancer Diagnostics. Clinical Protocol Associated With Cancer of the Breast. Statut inconnu 21 novembre 2023
NCT00334854 Localized Non-Rhabdomyosarcoma Soft Tissue Sarcomas Statut inconnu 21 novembre 2023
NCT00003122 Phase II Trial of Surgery as the Only Treatment for INSS Stage 2A & 2B Neuroblastoma Statut inconnu 21 novembre 2023
NCT03838718 REtroperitoneal SArcoma Registry (RESAR): Prospective Collection of Primary Retroperitoneal Sarcoma Patient's Data, Radiological and Pathological Material for the TransAtlantic Retroperitoneal Sarcoma Working Group (RESAR) En recrutement 21 novembre 2023
NCT01704716 High Risk Neuroblastoma Study 1 of SIOP-Europe (SIOPEN) En recrutement 21 novembre 2023
NCT05376891 Disease Registry on Patients With Advanced NSCLC Harboring METex14 Skipping Alterations (MOMENT) En recrutement 21 novembre 2023
NCT02885753 Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver (OSCAR) En recrutement 21 novembre 2023
NCT01620372 Constitution d'Une Cohorte Nationale rétrospective de Survivants d'un Cancer Solide de l'Enfant diagnostiqué Avant 2000 (FCCSS) En recrutement 21 novembre 2023
NCT01197924 Médulloblastome of the Child and After-effects Cognitive: Study Anatomo-functional by IRM of the Working Memory (MEDIR) Statut inconnu 21 novembre 2023
NCT02857699 Prospective Observational Study to Investigate the Added Value of the Health Related Quality of Life and Patient Reported Symptoms in the Identification of the Recommended Phase II Dose in Phase I Trials of Molecularly Targeted Therapies. (QoL Phase I) Statut inconnu 21 novembre 2023
NCT04987476 Hétérogénéité Des Tumeurs Rhabdoides : Approches en " Cellules Uniques " Pour Identifier Des Cibles thérapeutiques (InnovRT-2) En recrutement 21 novembre 2023
NCT05554432 Development of an EORTC Immune Checkpoint Inhibitor-specific Quality of Life Item List: Phase 1 & 2 (EORTC ICI) En recrutement 21 novembre 2023
NCT05989191 An International Field Study for the Reliability and Validity of the EORTC PATSAT-C33 and the EORTC OUT-PATSAT7 Questionnaires (PATSAT) En recrutement 21 novembre 2023
NCT05272358 Economic Evaluation of Early Management of Sarcoma Patients by the Sarcoma Reference Network (NETSARC), Exploration of Organisational and Financial Constraints (OPTISARC) Statut inconnu 21 novembre 2023
NCT03275311 Epidemiological Strategy and Medical Economic (ESME) Research Program / Academic Real World Data Platform: Evolution of the Therapeutic Care in Metastatic Breast Cancer Across the French Comprehensive Cancer Centers From 2008 (ESME-MBC) En recrutement 20 mars 2023
NCT03275311 Epidemiological Strategy and Medical Economic (ESME) Research Program / Academic Real World Data Platform: Evolution of the Therapeutic Care in Metastatic Breast Cancer Across the French Comprehensive Cancer Centers From 2008 (ESME-MBC) En recrutement 20 mars 2023
NCT03848052 Epidemiological Strategy and Medical Economic (ESME) Research Program / Academic Real World Data Platform: Evolution of the Therapeutic Care in Lung Cancer in France Since 2015 En recrutement 05 novembre 2022
NCT03848052 Epidemiological Strategy and Medical Economic (ESME) Research Program / Academic Real World Data Platform: Evolution of the Therapeutic Care in Lung Cancer in France Since 2015 En recrutement 05 novembre 2022
NCT01361100 Evaluation of the Oncoral® Test in Epidermoid Carcinomas of the Upper Aerodigestive Tract Statut inconnu 29 octobre 2022

Listes des établissements rattachés

Finess Etablissement Catégorie Adress
750160012 CLCC INSTITUT CURIE Centre de Lutte Contre Cancer 26 R D ULM 75248 PARIS CEDEX 05
910813732 CLCC DE PROTONTHERAPIE ORSAY Centre de Lutte Contre Cancer BAT 101 91898 ORSAY CEDEX
920000460 CLCC RENE HUGUENIN INSTITUT CURIE Centre de Lutte Contre Cancer 35 R DAILLY 92210 ST CLOUD